Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis. (Q38847178)

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20 February 2020

title

Cdk8 deletion in the Apc(Min) murine tumour model represses EZH2 activity and accelerates tumourigenesis (English)

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7

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8

Merone Roose-Girma

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20 February 2020

author name string

Mark L McCleland

1

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20 February 2020

Tim M Soukup

2

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20 February 2020

Scot D Liu

3

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20 February 2020

Jonathan H Esensten

4

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20 February 2020

Felipe de Sousa e Melo

5

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20 February 2020

Murat Yaylaoglu

6

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Ron Firestein

9

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publication date

24 September 2015

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20 February 2020

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20 February 2020

volume

237

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issue

4

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page(s)

508-519

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Orchestrated response: a symphony of transcription factors for gene control

20 February 2020

cites work

1 reference

The Mediator complex and transcription regulation

21 January 2018

1 reference

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction

21 January 2018

1 reference

Mediator structural conservation and implications for the regulation mechanism

21 January 2018

1 reference

Mechanisms of Mediator complex action in transcriptional activation.

21 January 2018

1 reference

Mediator--a universal complex in transcriptional regulation

21 January 2018

1 reference

Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action

21 January 2018

1 reference

Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice

21 January 2018

1 reference

The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development

21 January 2018

1 reference

A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

21 January 2018

1 reference

A kinase-cyclin pair in the RNA polymerase II holoenzyme.

21 January 2018

1 reference

Dissecting the regulatory circuitry of a eukaryotic genome

21 January 2018

1 reference

Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

21 January 2018

1 reference

Cdk8 is essential for preimplantation mouse development

21 January 2018

1 reference

Dysregulation of CDK8 and Cyclin C in tumorigenesis

21 January 2018

1 reference

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

21 January 2018

1 reference

Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.

21 January 2018

1 reference

Mediator is a transducer of Wnt/beta-catenin signaling.

21 January 2018

1 reference

E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8

21 January 2018

1 reference

Components of the transcriptional Mediator complex are required for asymmetric cell division in C. elegans

21 January 2018

1 reference

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8.

21 January 2018

1 reference

Cyclin C is a haploinsufficient tumour suppressor

21 January 2018

1 reference

Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India

21 January 2018

1 reference

The use of genetic programming in the analysis of quantitative gene expression profiles for identification of nodal status in bladder cancer

21 January 2018

1 reference

Tumor-suppressive effects of CDK8 in endometrial cancer cells.

21 January 2018

1 reference

A highly efficient recombineering-based method for generating conditional knockout mutations

21 January 2018

1 reference

Zfp423 is required for normal cerebellar development

21 January 2018

1 reference

Simple and highly efficient BAC recombineering using galK selection

21 January 2018

1 reference

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

Lymph node-independent liver metastasis in a model of metastatic colorectal cancer

21 January 2018

1 reference

Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice

21 January 2018

1 reference

RNA-guided human genome engineering via Cas9

21 January 2018

1 reference

An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

21 January 2018

1 reference

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

21 January 2018

1 reference

Automatic nuclei segmentation in H&E stained breast cancer histopathology images

21 January 2018

1 reference

Automated selection of DAB-labeled tissue for immunohistochemical quantification.

21 January 2018

1 reference

Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

1 reference

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

21 January 2018

1 reference

Phosphorylation of serine 10 in histone H3, what for?

21 January 2018

1 reference

Multiplex genome engineering using CRISPR/Cas systems

21 January 2018

1 reference

Bone morphogenetic protein signalling in colorectal cancer.

21 January 2018

1 reference

The R-spondin protein family

21 January 2018

1 reference

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells

21 January 2018

1 reference

LHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer

21 January 2018

1 reference

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.

21 January 2018

1 reference

Loss of SFRP1 expression is associated with aberrant beta-catenin distribution and tumor progression in mucoepidermoid carcinoma of salivary glands

21 January 2018

1 reference

PAF and EZH2 induce Wnt/β-catenin signaling hyperactivation

21 January 2018

1 reference

A new world of Polycombs: unexpected partnerships and emerging functions

21 January 2018

1 reference

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

21 January 2018

1 reference

The C. elegans CDK8 Mediator module regulates axon guidance decisions in the ventral nerve cord and during dorsal axon navigation

21 January 2018

1 reference

NF-kappaB: tumor promoter or suppressor?

21 January 2018

1 reference

Duel nature of TGF-beta signaling: tumor suppressor vs. tumor promoter

21 January 2018

1 reference

The Mediator complex: a master coordinator of transcription and cell lineage development

21 January 2018

1 reference

A genetic screen identifies novel polycomb group genes in Drosophila

21 January 2018

1 reference

Mediator CDK subunits are platforms for interactions with various chromatin regulatory complexes.

21 January 2018

1 reference

Colorectal cancer screening: prospects for molecular stool analysis

21 January 2018

1 reference

Progression from colorectal adenoma to carcinoma is associated with non-random chromosomal gains as detected by comparative genomic hybridisation

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.4596

1 reference

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release_5wqejqbvlzbfrlcyijpz3kaj7q

20 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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