MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles (Q38873955)

7 September 2017

MiR-21 is required for anti-tumor immune response in mice: an implication for its bi-directional roles (English)

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7 September 2017

W He

1

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7 September 2017

C Wang

2

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7 September 2017

R Mu

3

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7 September 2017

P Liang

4

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7 September 2017

Z Huang

5

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7 September 2017

J Zhang

6

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7 September 2017

L Dong

7

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7 September 2017

language of work or name

English

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publication date

27 March 2017

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7 September 2017

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7 September 2017

36

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29

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7 September 2017

4212-4223

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https://scigraph.springernature.com/pub.10.1038/onc.2017.62

7 September 2017

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Comparative effect of two pan-class I PI3K inhibitors used as anticancer drugs on human T cell function

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miRNA oligonucleotide and sponge for miRNA-21 inhibition mediated by PEI-PLL in breast cancer therapy

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MicroRNA-21 promotes cell proliferation, migration, and resistance to apoptosis through PTEN/PI3K/AKT signaling pathway in esophageal cancer

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Upregulation of miR-21 in cisplatin resistant ovarian cancer via JNK-1/c-Jun pathway

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Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction

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Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma.

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miRNA profiling of naïve, effector and memory CD8 T cells.

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MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1.

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Tumors Escape CD4+ T-cell-Mediated Immunosurveillance by Impairing the Ability of Infiltrating Macrophages to Indirectly Present Tumor Antigens

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Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth

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Glutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation

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Allo-transplantation of mesenchymal stem cells attenuates hepatic injury through IL1Ra dependent macrophage switch in a mouse model of liver disease

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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MicroRNA-21 promotes Th17 differentiation and mediates experimental autoimmune encephalomyelitis

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MicroRNA-21 deficiency protects from lupus-like autoimmunity in the chronic graft-versus-host disease model of systemic lupus erythematosus.

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MicroRNA-21 with therapeutic potential in autoimmune diseases

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miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.

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The autoregulatory feedback loop of microRNA-21/programmed cell death protein 4/activation protein-1 (MiR-21/PDCD4/AP-1) as a driving force for hepatic fibrosis development

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miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

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Silencing of microRNA-21 in vivo ameliorates autoimmune splenomegaly in lupus mice

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

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The oncogenic microRNA miR-21 promotes regulated necrosis in mice

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MicroRNAs control hepatocyte proliferation during liver regeneration

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microRNA-21 promotes osteogenic differentiation of mesenchymal stem cells by the PI3K/β-catenin pathway.

21 January 2018

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miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells

21 January 2018

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Hallmarks of Cancer: The Next Generation

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Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

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Requirement of the NF-kappaB subunit p65/RelA for K-Ras-induced lung tumorigenesis

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The mutational landscape of head and neck squamous cell carcinoma

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Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells

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Autologous HER2 CMV bispecific CAR T cells are safe and demonstrate clinical benefit for glioblastoma in a Phase I trial

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CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy

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Over-expressing Akt in T cells to resist tumor immunosuppression and increase anti-tumor activity

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Big opportunities for small molecules in immuno-oncology

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From monoclonal antibodies to small molecules: the development of inhibitors targeting the PD-1/PD-L1 pathway

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Adoptive T-Cell Therapy for Cancer

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Adoptive cell transfer as personalized immunotherapy for human cancer

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MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.

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MicroRNA-155 is required for effector CD8+ T cell responses to virus infection and cancer

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Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel

21 January 2018

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Enhanced antitumor and reduced toxicity effect of Schisanreae polysaccharide in 5-Fu treated Heps-bearing mice

21 January 2018

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T-cell Activation Induces Dynamic Changes in miRNA Expression Patterns in CD4 and CD8 T-cell Subsets

21 January 2018

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In vivo programming of tumor antigen-specific T lymphocytes from pluripotent stem cells to promote cancer immunosurveillance

31 March 2020

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miR-21 Regulates Skin Wound Healing by Targeting Multiple Aspects of the Healing Process

31 March 2020

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T cell-NF-κB activation is required for tumor control in vivo

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2017.62

MiR-21 regulates adipogenic differentiation through the modulation of TGF-beta signaling in mesenchymal stem cells derived from human adipose tissue

31 March 2020

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12 December 2020

Role of PI3K/Akt signaling in memory CD8 T cell differentiation

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12 December 2020

Human ovarian tumor ascites fluids rapidly and reversibly inhibit T cell receptor-induced NF-κB and NFAT signaling in tumor-associated T cells

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12 December 2020

Mechanism of T cell regulation by microRNAs

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12 December 2020

Identifiers

DOI

10.1038/ONC.2017.62

1 reference

Dimensions Publication ID

7 September 2017

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1 reference