FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection (Q38920991)

7 September 2017

FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection (English)

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7 September 2017

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11

Qi Shi

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7 September 2017

12

Xiao-Ping Dong

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7 September 2017

Yin Xu

1

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7 September 2017

Chan Tian

2

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7 September 2017

Jing Sun

3

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7 September 2017

Jin Zhang

4

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7 September 2017

Ke Ren

5

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7 September 2017

Xue-Yu Fan

6

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7 September 2017

Ke Wang

7

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7 September 2017

Hui Wang

8

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7 September 2017

Yu-E Yan

9

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7 September 2017

Cao Chen

10

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7 September 2017

13 January 2015

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7 September 2017

Molecular Neurobiology

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7 September 2017

53

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7 September 2017

1

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7 September 2017

706-719

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https://scigraph.springernature.com/pub.10.1007/s12035-014-9028-7

7 September 2017

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1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Generating a prion with bacterially expressed recombinant prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

XBP-1u suppresses autophagy by promoting the degradation of FoxO1 in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Autophagy is a part of ultrastructural synaptic pathology in Creutzfeldt-Jakob disease: a brain biopsy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Autophagy induction by trehalose counteracts cellular prion infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Lithium induces clearance of protease resistant prion protein in prion-infected cells by induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Rheb binds and regulates the mTOR kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Autophagy in viral replication and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

mTOR signaling in growth control and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Spatial coupling of mTOR and autophagy augments secretory phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Import of a cytosolic protein into lysosomes by chaperone-mediated autophagy depends on its folding state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Prions and their partners in crime

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Subclinical prion infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-014-9028-7

Neuronal autophagy in experimental scrapie

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25579381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25579381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12035-014-9028-7

1 reference

Dimensions Publication ID

7 September 2017

1026642461

0 references

Fatcat ID

release_zpvvpoptxrbl7ngyifdxtgg36m

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zpvvpoptxrbl7ngyifdxtgg36m

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference