Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase. (Q38939325)

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English	Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase.	scientific article

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23 February 2020

Resistance to UV-induced apoptosis by β-HPV5 E6 involves targeting of activated BAK for proteolysis by recruitment of the HERC1 ubiquitin ligase (English)

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23 February 2020

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23 February 2020

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23 February 2020

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Amy Holloway

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23 February 2020

Mark Simmonds

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23 February 2020

Abul Azad

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15 December 2014

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23 February 2020

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International Journal of Cancer

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23 February 2020

136

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23 February 2020

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23 February 2020

2831-2843

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23 February 2020

Detection of human papillomavirus DNA in cutaneous squamous cell carcinoma among immunocompetent individuals

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Increased risk of skin cancer associated with the presence of epidermodysplasia verruciformis human papillomavirus types in normal skin

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Human papillomavirus infection and non-melanoma skin cancer in immunosuppressed and immunocompetent individuals.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Beta-papillomavirus DNA loads in hair follicles of immunocompetent people and organ transplant recipients

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Human papillomavirus load in eyebrow hair follicles and risk of cutaneous squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

HPV-associated skin disease.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Cutaneous HPV5 E6 causes increased expression of Osteoprotegerin and Interleukin 6 which contribute to evasion of UV-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

The human papillomavirus 16 E6 protein binds to Fas-associated death domain and protects cells from Fas-triggered apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Accelerated degradation of FADD and procaspase 8 in cells expressing human papilloma virus 16 E6 impairs TRAIL-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Reduced apoptotic levels in squamous but not basal cell carcinomas correlates with detection of cutaneous human papillomavirus

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Human papillomavirus (HPV) E6 interactions with Bak are conserved amongst E6 proteins from high and low risk HPV types

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Role of HPV E6 proteins in preventing UVB-induced release of pro-apoptotic factors from the mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

The role of the E6-p53 interaction in the molecular pathogenesis of HPV.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Identification of the regions of the HPV 5 E6 protein involved in Bak degradation and inhibition of apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

E6 proteins from diverse cutaneous HPV types inhibit apoptosis in response to UV damage

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Development of a bicistronic vector driven by the human polypeptide chain elongation factor 1alpha promoter for creation of stable mammalian cell lines that express very high levels of recombinant proteins

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Blockade of the BAK hydrophobic groove by inhibitory phosphorylation regulates commitment to apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Tyrosine dephosphorylation is required for Bak activation in apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

A new quantitative assay for cytochrome c release in apoptotic cells.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

The Bad guy cooperates with good cop p53: Bad is transcriptionally up-regulated by p53 and forms a Bad/p53 complex at the mitochondria to induce apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

BAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic groove

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Regulation of the human papillomavirus type 18 E6/E6AP ubiquitin ligase complex by the HECT domain-containing protein EDD.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

BH3-ligand regulates access of MCL-1 to its E3 ligase

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Bcl-2 family interaction with the mitochondrial morphogenesis machinery

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.29350

21 January 2018

Identifiers

10.1002/IJC.29350

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25408501%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25408501%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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