Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage-bone crosstalk (Q38960505)

8 September 2017

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title

Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage-bone crosstalk (English)

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8 September 2017

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1

Steven R Goldring

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8 September 2017

2

Mary B Goldring

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PubMed ID

27652499

8 September 2017

language of work or name

English

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publication date

22 September 2016

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Nature Reviews Rheumatology

8 September 2017

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8 September 2017

12

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8 September 2017

632-644

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8 September 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2016.148

8 September 2017

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The role of bone in osteoarthritis pathogenesis

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Subchondral bone changes in hand and knee osteoarthritis detected by radiography

21 January 2018

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A 2 yr longitudinal radiographic study examining the effect of a bisphosphonate (risedronate) upon subchondral bone loss in osteoarthritic knee patients

21 January 2018

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Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy

21 January 2018

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99mTc HMDP bone scanning in generalised nodal osteoarthritis. II. The four hour bone scan image predicts radiographic change

21 January 2018

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Clinical value of (99m)Tc-methylene diphosphonate (MDP) bone single photon emission computed tomography (SPECT) in patients with knee osteoarthritis

21 January 2018

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Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation

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Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention

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Meniscectomy leads to an early increase in subchondral bone plate thickness in the rabbit knee

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Assessment of cortical and trabecular bone changes in two models of post-traumatic osteoarthritis

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In vivo cyclic compression causes cartilage degeneration and subchondral bone changes in mouse tibiae

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Finite element studies of some juxtarticular stress changes due to localized subchondral stiffening.

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Transient osteoporosis: transient bone marrow edema?

21 January 2018

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Bone marrow edema pattern in advanced hip osteoarthritis: quantitative assessment with magnetic resonance imaging and correlation with clinical examination, radiographic findings, and histopathology

21 January 2018

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Advanced hip osteoarthritis: magnetic resonance imaging aspects and histopathology correlations.

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Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings.

21 January 2018

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Presence of MRI-detected joint effusion and synovitis increases the risk of cartilage loss in knees without osteoarthritis at 30-month follow-up: the MOST study

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What comes first? Multitissue involvement leading to radiographic osteoarthritis: magnetic resonance imaging-based trajectory analysis over four years in the osteoarthritis initiative

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Increase in bone marrow lesions associated with cartilage loss: A longitudinal magnetic resonance imaging study of knee osteoarthritis

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Bone marrow edema and its relation to progression of knee osteoarthritis.

21 January 2018

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The association of bone attrition with knee pain and other MRI features of osteoarthritis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Osteocytes: master orchestrators of bone

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21 January 2018

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Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo.

21 January 2018

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Osteocyte signaling in bone

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Cysts, geodes, and erosions

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Subchondral cystlike lesions develop longitudinally in areas of bone marrow edema-like lesions in patients with or at risk for knee osteoarthritis: detection with MR imaging--the MOST study

21 January 2018

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Contrast-enhanced MRI of subchondral cysts in patients with or at risk for knee osteoarthritis: the MOST study

21 January 2018

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The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study

21 January 2018

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Bone marrow lesions can be subtyped into groups with different clinical outcomes using two magnetic resonance imaging (MRI) sequences

21 January 2018

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Osteophytes, juxta-articular radiolucencies and cancellous bone changes in the proximal tibia of patients with knee osteoarthritis

21 January 2018

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Osteophytes and progression of knee osteoarthritis

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Osteoblast-chondrocyte interactions in osteoarthritis

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Chondrocyte survival in articular cartilage: the influence of subchondral bone in a bovine model.

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Subchondral bone osteoblasts induce phenotypic changes in human osteoarthritic chondrocytes.

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Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone.

21 January 2018

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Gene expression analyses of subchondral bone in early experimental osteoarthritis by microarray

21 January 2018

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Genome-wide expression profiles of subchondral bone in osteoarthritis

21 January 2018

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Osteoblast-like cells from human subchondral osteoarthritic bone demonstrate an altered phenotype in vitro: possible role in subchondral bone sclerosis

21 January 2018

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New developments in osteoarthritis. Posttraumatic osteoarthritis: pathogenesis and pharmacological treatment options

21 January 2018

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Future therapeutics for osteoarthritis

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The future of osteoarthritis therapeutics: emerging biological therapy

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The future of osteoarthritis therapeutics: targeted pharmacological therapy

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Emerging targets in osteoarthritis therapy.

21 January 2018

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The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?

21 January 2018

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New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine?

21 January 2018

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Post-traumatic osteoarthritis: from mouse models to clinical trials

21 January 2018

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Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]

21 January 2018

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Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthri

21 January 2018

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Relationships between biochemical markers of bone and cartilage degradation with radiological progression in patients with knee osteoarthritis receiving risedronate: the Knee Osteoarthritis Structural Arthritis randomized clinical trial

21 January 2018

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Zoledronic acid reduces knee pain and bone marrow lesions over 1 year: a randomised controlled trial

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Emerging drugs for osteoarthritis

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Osteoarthritis year in review 2015: soluble biomarkers and the BIPED criteria

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OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis.

21 January 2018

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Imaging research results from the osteoarthritis initiative (OAI): a review and lessons learned 10 years after start of enrolment

21 January 2018

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Biomechanical factors in osteoarthritis: the effects of joint instability

21 January 2018

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A systems view of risk factors for knee osteoarthritis reveals insights into the pathogenesis of the disease

21 January 2018

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Metabolic stress-induced joint inflammation and osteoarthritis

21 January 2018

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Effects of mechanical loading on the tissues of the rabbit knee

21 January 2018

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Editorial: [Hot Topic: Epigenetics in Arthritis]

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21 January 2018

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Angiogenesis in the synovium and at the osteochondral junction in osteoarthritis

21 January 2018

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Etiology of osteoarthritis: genetics and synovial joint development

21 January 2018

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31 March 2020

Consider the tidemark

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Role of bone in osteoarthritis pathogenesis

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Histopathological correlation of cartilage swelling detected by magnetic resonance imaging in early experimental osteoarthritis

31 March 2020

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Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

31 March 2020

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Collagens and cartilage matrix homeostasis.

31 March 2020

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Primary cilia in osteoarthritic chondrocytes: from chondrons to clusters

31 March 2020

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Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction

31 March 2020

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Proteoglycan 4 expression protects against the development of osteoarthritis

31 March 2020

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Subchondral bone changes in three different canine models of osteoarthritis

31 March 2020

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Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis

31 March 2020

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Characterizing a novel and adjustable noninvasive murine joint loading model

31 March 2020

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MRI-based semiquantitative assessment of subchondral bone marrow lesions in osteoarthritis research

31 March 2020

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Osteoarthritic bone marrow lesions almost exclusively colocate with denuded cartilage: a 3D study using data from the Osteoarthritis Initiative

31 March 2020

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Increased intracortical remodeling following fatigue damage

31 March 2020

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MRI of bone marrow edema-like signal in the pathogenesis of subchondral cysts

31 March 2020

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The bone cysts of osteoarthritis

31 March 2020

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The cysts of osteoarthritis of the hip; a radiological and pathological study

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Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Apparent spontaneous joint restoration in hip osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

The effect of marginal osteophytes on reduction of varus-valgus instability in osteoarthritic knees

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Needs and opportunities in the assessment and treatment of osteoarthritis of the knee and hip: the view of the rheumatologist

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Treatment of symptomatic knee osteoarthritis with oral salmon calcitonin: results from two phase 3 trials

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

Progressive cell-mediated changes in articular cartilage and bone in mice are initiated by a single session of controlled cyclic compressive loading

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2016.148

The permeability of articular cartilage

31 March 2020

1 reference

12 December 2020

Microcracks in articular calcified cartilage of human femoral heads

1 reference

12 December 2020

Role of subchondral bone in the initiation and progression of cartilage damage.

1 reference

12 December 2020

Proliferative remodeling of the spatial organization of human superficial chondrocytes distant from focal early osteoarthritis

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12 December 2020

Within-subregion relationship between bone marrow lesions and subsequent cartilage loss in knee osteoarthritis

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12 December 2020

Subchondral bone failure in overload arthrosis: a scanning electron microscopic study in horses

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12 December 2020

Periarticular osteoporosis in osteoarthritis of the knee.

1 reference

12 December 2020

The enthesis organ concept and its relevance to the spondyloarthropathies

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12 December 2020

Microcracks in the calcified layer of articular cartilage

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12 December 2020

Mechanical and biochemical properties of human articular cartilage in osteoarthritic femoral heads and in autopsy specimens

1 reference

12 December 2020

Facilitative glucose transporters in articular chondrocytes. Expression, distribution and functional regulation of GLUT isoforms by hypoxia, hypoxia mimetics, growth factors and pro-inflammatory cytokines.

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12 December 2020

Adaptation of subchondral bone in osteoarthritis.

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12 December 2020

The vascularity and remodelling of subchondrial bone and calcified cartilage in adult human femoral and humeral heads. An age- and stress-related phenomenon

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12 December 2020

Induction of high temperature requirement A1, a serine protease, by TGF-beta1 in articular chondrocytes of mouse models of OA.

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2016.148

1 reference

PubMed ID

27652499

Dimensions Publication ID

8 September 2017

0 references

1 reference

PubMed ID

27652499