New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine? (Q38138598)

29 August 2017

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New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine? (English)

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29 August 2017

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personalized medicine

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based on heuristic

inferred from title

author

Johanne Martel-Pelletier

series ordinal

3

object named as

Johanne Martel-Pelletier

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PubMed ID

24044485

29 August 2017

Jean-Pierre Pelletier

series ordinal

2

object named as

Jean-Pierre Pelletier

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29 August 2017

1

Camille Roubille

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PubMed ID

24044485

29 August 2017

language of work or name

English

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publication date

1 October 2013

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Expert Opinion on Pharmacotherapy

29 August 2017

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29 August 2017

14

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29 August 2017

15

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29 August 2017

2059-2077

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Chondrogenesis, chondrocyte differentiation, and articular cartilage metabolism in health and osteoarthritis

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Regeneration of articular cartilage chondral defects by osteogenic protein-1 (bone morphogenetic protein-7) in sheep

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Phase 1 safety and tolerability study of BMP-7 in symptomatic knee osteoarthritis

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Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis

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Platelet-rich plasma therapy - future or trend?

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Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis: a prospective, double-blind, randomized trial.

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Platelet-rich plasma intra-articular injection versus hyaluronic acid viscosupplementation as treatments for cartilage pathology: from early degeneration to osteoarthritis.

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Injection of platelet-rich plasma in patients with primary and secondary knee osteoarthritis: a pilot study

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Platelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: study design and preliminary results of a randomized controlled trial

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A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee osteoarthritis.

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Future therapeutics for osteoarthritis

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Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase.

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Multilineage potential of adult human mesenchymal stem cells

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A stem cell-based approach to cartilage repair.

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Stem cell therapy in a caprine model of osteoarthritis

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Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit.

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Antiinflammatory and chondroprotective effects of intraarticular injection of adipose-derived stem cells in experimental osteoarthritis.

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Long-term detection of human adipose-derived mesenchymal stem cells after intraarticular injection in SCID mice

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Treatment of a full-thickness articular cartilage defect in the femoral condyle of an athlete with autologous bone-marrow stromal cells

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Mesenchymal stem cell therapy for knee osteoarthritis. Preliminary report of four patients.

21 January 2018

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Isolation of adipose-derived stem cells and their induction to a chondrogenic phenotype.

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Mesenchymal stem cells for the treatment of cartilage lesions: from preclinical findings to clinical application in orthopaedics

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Chondrogenic differentiation of adipose tissue-derived mesenchymal stem cells: greater doses of growth factor are necessary

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A comparison between the chondrogenic potential of human bone marrow stem cells (BMSCs) and adipose-derived stem cells (ADSCs) taken from the same donors.

21 January 2018

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Mesenchymal stem cells in osteoarticular diseases.

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Obesity short-circuits stemness gene network in human adipose multipotent stem cells.

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Osteochondral alterations in osteoarthritis

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Targeting subchondral bone for treating osteoarthritis: what is the evidence?

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Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model

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The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis

21 January 2018

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Effect of risedronate on joint structure and symptoms of knee osteoarthritis: results of the BRISK randomized, controlled trial [ISRCTN01928173]

21 January 2018

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Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthri

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Strontium ranelate inhibits key factors affecting bone remodeling in human osteoarthritic subchondral bone osteoblasts

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Strontium ranelate increases cartilage matrix formation

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Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium.

21 January 2018

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Effects of strontium ranelate on spinal osteoarthritis progression.

21 January 2018

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Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double-blind, randomised placebo-controlled trial

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Impact of treatments for osteoporosis on osteoarthritis progression

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New perspective in osteoarthritis: the OPG and RANKL system as a potential therapeutic target?

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Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis

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Denosumab, a new pharmacotherapy option for postmenopausal osteoporosis

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Teriparatide as a chondroregenerative therapy for injury-induced osteoarthritis.

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Effects of calcitonin on knee osteoarthritis and quality of life

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Safety concerns with the long-term management of osteoporosis

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Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trial

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Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial

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Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

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IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort

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Erosive osteoarthritis of the hand: clinical experience with anakinra.

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A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

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Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy

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Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial

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Autologous conditioned serum (Orthokine) is an effective treatment for knee osteoarthritis

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Treatment of erosive osteoarthritis of the hands by intra-articular infliximab injections: a pilot study

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Tumour necrosis factor blockade for the treatment of erosive osteoarthritis of the interphalangeal finger joints: a double blind, randomised trial on structure modification

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Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee.

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Biologic agents in osteoarthritis: hopes and disappointments

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The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

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Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis.

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Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage.

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Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice.

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Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!).

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In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

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Effective reduction of the interleukin-1β transcript in osteoarthritis-prone guinea pig chondrocytes via short hairpin RNA mediated RNA interference influences gene expression of mediators implicated in disease pathogenesis

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Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-kappaBp65-specific siRNA.

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MicroRNAs: genomics, biogenesis, mechanism, and function

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MiR-194 regulates chondrogenic differentiation of human adipose-derived stem cells by targeting Sox5

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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

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Expression of MicroRNA-146a in osteoarthritis cartilage

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Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

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Platelet-rich plasma: intra-articular knee injections produced favorable results on degenerative cartilage lesions

21 January 2018

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10.1517/14656566.2013.825606

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference

PubMed ID

24044485