VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. (Q54543688)

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English	VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival.	scientific article

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scholarly article

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

VEGF-independent cell-autonomous functions of HIF-1α regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. (English)

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

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Elisa Araldi

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Europe PubMed Central

31 May 2018

Amato J. Giaccia

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object named as

Amato J Giaccia

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

author name string

Christa Maes

1

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Katharina Haigh

3

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Richa Khatri

4

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Riet Van Looveren

5

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Jody J Haigh

7

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Geert Carmeliet

8

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Ernestina Schipani

9

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

publication date

1 March 2012

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

Journal of Bone and Mineral Research

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

27

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http://europepmc.org/abstract/MED/22162090

596-609

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http://europepmc.org/abstract/MED/22162090

3

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Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

The complexities of skeletal biology

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Developmental regulation of the growth plate

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Molecular mechanisms of endochondral bone development.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Transcriptional control of chondrocyte fate and differentiation

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels.

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF1alpha regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Hif-1alpha regulates differentiation of limb bud mesenchyme and joint development.

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Hypoxia, HIFs and bone development

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

A conserved family of prolyl-4-hydroxylases that modify HIF

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https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The role of oxygen availability in embryonic development and stem cell function

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The biology of VEGF and its receptors

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

VEGFA is necessary for chondrocyte survival during bone development

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Expression of VEGF isoforms by epiphyseal chondrocytes during low-oxygen tension is HIF-1 alpha dependent.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Induction of phosphoglycerate kinase 1 gene expression by hypoxia. Roles of Arnt and HIF1alpha

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The hypoxic tumor microenvironment and gene expression

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The biology of hypoxia: the role of oxygen sensing in development, normal function, and disease

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The role of hypoxia in development of the Mammalian embryo

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.1487

21 January 2018

Identifiers

10.1002/JBMR.1487

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

1 reference

Europe PubMed Central

31 May 2018

http://europepmc.org/abstract/MED/22162090

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