From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking (Q38971505)

8 September 2017

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title

From the endoplasmic reticulum to the plasma membrane: mechanisms of CFTR folding and trafficking (English)

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8 September 2017

main subject

endoplasmic reticulum

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Carlos M Farinha

1

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author name string

Sara Canato

series ordinal

2

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8 September 2017

language of work or name

1 reference

3 October 2016

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Cellular and Molecular Life Sciences

8 September 2017

published in

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8 September 2017

volume

74

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8 September 2017

issue

1

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8 September 2017

page(s)

39-55

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Cystic fibrosis: molecular biology and therapeutic implications

8 September 2017

cites work

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CFTR function and prospects for therapy

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Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi

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Most F508del-CFTR is targeted to degradation at an early folding checkpoint and independently of calnexin

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Alteration of CFTR transmembrane span integration by disease-causing mutations

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Sequence-specific retention and regulated integration of a nascent membrane protein by the endoplasmic reticulum Sec61 translocon

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Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue.

21 January 2018

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Sequential triage of transmembrane segments by Sec61alpha during biogenesis of a native multispanning membrane protein

21 January 2018

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Membrane-integration characteristics of two ABC transporters, CFTR and P-glycoprotein

21 January 2018

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Folding of CFTR is predominantly cotranslational

21 January 2018

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Ligand-driven vectorial folding of ribosome-bound human CFTR NBD1

21 January 2018

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Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function

21 January 2018

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Cooperative assembly and misfolding of CFTR domains in vivo.

21 January 2018

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Processing mutations disrupt interactions between the nucleotide binding and transmembrane domains of P-glycoprotein and the cystic fibrosis transmembrane conductance regulator (CFTR).

21 January 2018

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

21 January 2018

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Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

21 January 2018

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Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure

21 January 2018

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Alteration of the cystic fibrosis transmembrane conductance regulator folding pathway

21 January 2018

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Deletion of Phe508 in the first nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator increases its affinity for the heat shock cognate 70 chaperone

21 January 2018

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Restoration of NBD1 thermal stability is necessary and sufficient to correct ∆F508 CFTR folding and assembly

21 January 2018

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The primary folding defect and rescue of ΔF508 CFTR emerge during translation of the mutant domain

21 January 2018

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The cystic fibrosis-causing mutation deltaF508 affects multiple steps in cystic fibrosis transmembrane conductance regulator biogenesis.

21 January 2018

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Revertants, low temperature, and correctors reveal the mechanism of F508del-CFTR rescue by VX-809 and suggest multiple agents for full correction.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The V510D suppressor mutation stabilizes DeltaF508-CFTR at the cell surface.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Revertant mutants G550E and 4RK rescue cystic fibrosis mutants in the first nucleotide-binding domain of CFTR by different mechanisms

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A chaperone trap contributes to the onset of cystic fibrosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Endoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Gp78 cooperates with RMA1 in endoplasmic reticulum-associated degradation of CFTRDeltaF508.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A di-acidic signal required for selective export from the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Atypical activation of the unfolded protein response in cystic fibrosis airway cells contributes to p38 MAPK-mediated innate immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Regulatory crosstalk within the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Coupling cystic fibrosis to endoplasmic reticulum stress: Differential role of Grp78 and ATF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Five Percent of Normal Cystic Fibrosis Transmembrane Conductance Regulator mRNA Ameliorates the Severity of Pulmonary Disease in Cystic Fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Investigating Alternative Transport of Integral Plasma Membrane Proteins from the ER to the Golgi: Lessons from the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Golgi bypass: skirting around the heart of classical secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rescue of ΔF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Monomerization and ER Relocalization of GRASP Is a Requisite for Unconventional Secretion of CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

PDZ domain interaction controls the endocytic recycling of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Regulated recycling of mutant CFTR is partially restored by pharmacological treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Functional analysis of the C-terminal boundary of the second nucleotide binding domain of the cystic fibrosis transmembrane conductance regulator and structural implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Tissue-specific control of CFTR endocytosis by Dab2: Cargo recruitment as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The carboxyl terminus of the cystic fibrosis transmembrane conductance regulator binds to AP-2 clathrin adaptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Molecular motors and apical CFTR traffic in epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

ΔF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Disabled-2 protein facilitates assembly polypeptide-2-independent recruitment of cystic fibrosis transmembrane conductance regulator to endocytic vesicles in polarized human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rab11b regulates the apical recycling of the cystic fibrosis transmembrane conductance regulator in polarized intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

The relative binding affinities of PDZ partners for CFTR: a biochemical basis for efficient endocytic recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

PDZ domain proteins: scaffolds for signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

New insights into cystic fibrosis: molecular switches that regulate CFTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

HGF stimulation of Rac1 signaling enhances pharmacological correction of the most prevalent cystic fibrosis mutant F508del-CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Modulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CAL

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

VIP regulates CFTR membrane expression and function in Calu-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCε-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

EPAC1 activation by cAMP stabilizes CFTR at the membrane by promoting its interaction with NHERF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rescuing mutant CFTR: a multi-task approach to a better outcome in treating cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Cystic fibrosis F508del patients have apically localized CFTR in a reduced number of airway cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Peripheral protein quality control removes unfolded CFTR from the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

c-Cbl facilitates endocytosis and lysosomal degradation of cystic fibrosis transmembrane conductance regulator in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Rescue of DeltaF508-CFTR by the SGK1/Nedd4-2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Nedd4-2 does not regulate wt-CFTR in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

c-Cbl reduces stability of rescued ∆F508-CFTR in human airway epithelial cells: Implications for cystic fibrosis treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Small heat shock proteins target mutant cystic fibrosis transmembrane conductance regulator for degradation via a small ubiquitin-like modifier-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Non-native Conformers of Cystic Fibrosis Transmembrane Conductance Regulator NBD1 Are Recognized by Hsp27 and Conjugated to SUMO-2 for Degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Antagonistic regulation of cystic fibrosis transmembrane conductance regulator cell surface expression by protein kinases WNK4 and spleen tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

LMTK2-mediated phosphorylation regulates CFTR endocytosis in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Peptide microarray analysis of substrate specificity of the transmembrane Ser/Thr kinase KPI-2 reveals reactivity with cystic fibrosis transmembrane conductance regulator and phosphorylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Repairing the basic defect in cystic fibrosis - one approach is not enough.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Correctors of ΔF508 CFTR restore global conformational maturation without thermally stabilizing the mutant protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Mechanism-based corrector combination restores ΔF508-CFTR folding and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Increased efficacy of VX-809 in different cellular systems results from an early stabilization effect of F508del-CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Tgf-β1 inhibits Cftr biogenesis and prevents functional rescue of ΔF508-Cftr in primary differentiated human bronchial epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Pseudomonas aeruginosa Reduces VX-809 Stimulated F508del-CFTR Chloride Secretion by Airway Epithelial Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Mechanisms of CFTR Folding at the Endoplasmic Reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2387-7

Intracellular CFTR: localization and function

21 January 2018

1 reference

12 December 2020

Efficient endocytosis of the cystic fibrosis transmembrane conductance regulator requires a tyrosine-based signal

1 reference

12 December 2020

The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response

1 reference

12 December 2020

Co- and posttranslational translocation mechanisms direct cystic fibrosis transmembrane conductance regulator N terminus transmembrane assembly

1 reference

12 December 2020

Absence of typical unfolded protein response in primary cultured cystic fibrosis airway epithelial cells

1 reference

12 December 2020

Removal of multiple arginine-framed trafficking signals overcomes misprocessing of delta F508 CFTR present in most patients with cystic fibrosis

1 reference

12 December 2020

Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator

1 reference

12 December 2020

10.1007/S00018-016-2387-7

Identifiers

DOI

1 reference

release_kdpyl2ms6bewpiiryye3mrn23q

8 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kdpyl2ms6bewpiiryye3mrn23q

24 November 2022

mapped directly with Wikidata item

1 reference