HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice (Q38979985)

8 September 2017

title

HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice (English)

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8 September 2017

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Christopher J. Schofield

7

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10 June 2020

Omolara O Ogunshola

2

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10 June 2020

author name string

Ruoli L Chen

1

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10 June 2020

Karkheng K Yeoh

3

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10 June 2020

Anant Jani

4

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10 June 2020

Michalis Papadakis

5

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10 June 2020

Simon Nagel

6

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10 June 2020

Alastair M Buchan

8

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10 June 2020

language of work or name

English

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publication date

18 July 2014

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Journal of Neurochemistry

8 September 2017

number of pages

13

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based on heuristic

inferred from page(s)

published in

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10 June 2020

volume

131

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10 June 2020

issue

2

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10 June 2020

page(s)

177-189

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Structural basis for inhibition of the fat mass and obesity associated protein (FTO)

10 June 2020

cites work

1 reference

Maintaining blood-brain barrier integrity: pericytes perform better than astrocytes during prolonged oxygen deprivation.

21 January 2018

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Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia

21 January 2018

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Temperature-regulated model of focal ischemia in the mouse: a study with histopathological and behavioral outcomes

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Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

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Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure

21 January 2018

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Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD.

21 January 2018

1 reference

Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice

21 January 2018

1 reference

Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases

21 January 2018

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Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use.

21 January 2018

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Recombinant human erythropoietin in the treatment of acute ischemic stroke

21 January 2018

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Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism

21 January 2018

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Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease

21 January 2018

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Identification of hypoxia-induced genes in human SGBS adipocytes by microarray analysis.

21 January 2018

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Cerebral preconditioning and ischaemic tolerance

21 January 2018

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Erythropoietin increases neurogenesis and oligodendrogliosis of subventricular zone precursor cells after neonatal stroke

21 January 2018

1 reference

The updated biology of hypoxia-inducible factor

21 January 2018

1 reference

HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques

21 January 2018

1 reference

Hemorrhagic transformation after ischemic stroke in animals and humans

21 January 2018

1 reference

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

21 January 2018

1 reference

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

21 January 2018

1 reference

Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats

21 January 2018

1 reference

Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia

21 January 2018

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

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Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions

21 January 2018

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Desferoxamine preconditioning protects against cerebral ischemia in rats by inducing expressions of hypoxia inducible factor 1 alpha and erythropoietin

21 January 2018

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Expanding chemical biology of 2-oxoglutarate oxygenases

21 January 2018

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Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

21 January 2018

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Erythropoietin protects the in vitro blood-brain barrier against VEGF-induced permeability.

21 January 2018

1 reference

Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

21 January 2018

1 reference

Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats.

21 January 2018

1 reference

Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes.

21 January 2018

1 reference

Inhibition of prolyl hydroxylases by dimethyloxaloylglycine after stroke reduces ischemic brain injury and requires hypoxia inducible factor-1α.

21 January 2018

1 reference

Epo and non-hematopoietic cells: what do we know?

21 January 2018

1 reference

A new mathematical model for relative quantification in real-time RT-PCR

21 January 2018

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Regulation of angiogenesis by hypoxia: role of the HIF system

21 January 2018

1 reference

Translation of ischemic preconditioning to the patient: prolyl hydroxylase inhibition and hypoxia inducible factor-1 as novel targets for stroke therapy.

21 January 2018

1 reference

Inhibition of HIF prolyl-4-hydroxylases by FG-4497 reduces brain tissue injury and edema formation during ischemic stroke

21 January 2018

1 reference

F-actin cytoskeleton and sucrose permeability of immortalised rat brain microvascular endothelial cell monolayers: effects of cyclic AMP and astrocytic factors

21 January 2018

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Inhibition of 2-oxoglutarate dependent oxygenases

21 January 2018

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Plant Growth Regulator Daminozide Is a Selective Inhibitor of Human KDM2/7 Histone Demethylases

21 January 2018

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Oxygen sensing by HIF hydroxylases

21 January 2018

1 reference

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

21 January 2018

1 reference

Hypoxia-inducible factor prolyl 4-hydroxylase inhibition. A target for neuroprotection in the central nervous system

21 January 2018

1 reference

Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure.

21 January 2018

1 reference

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

21 January 2018

1 reference

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

21 January 2018

1 reference

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

21 January 2018

1 reference

Hypoxic preconditioning induces stroke tolerance in mice via a cascading HIF, sphingosine kinase, and CCL2 signaling pathway

21 January 2018

1 reference

The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.

21 January 2018

1 reference

Treatment of stroke with erythropoietin enhances neurogenesis and angiogenesis and improves neurological function in rats

21 January 2018

1 reference

Contribution of HIF-1alpha or HIF-2alpha to erythropoietin expression: in vivo evidence based on chromatin immunoprecipitation.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/JNC.12804

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24974727%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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