Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice. (Q39022770)

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scientific article published on 13 January 2017

Language	Label	Description	Also known as
English	Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice.	scientific article published on 13 January 2017

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scholarly article

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9 April 2020

Selective peroxisome proliferator-activated receptor-α modulator K-877 efficiently activates the peroxisome proliferator-activated receptor-α pathway and improves lipid metabolism in mice (English)

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9 April 2020

12

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9 April 2020

author name string

Kenta Takei

1

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9 April 2020

Song-Iee Han

2

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9 April 2020

Yuki Murayama

3

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9 April 2020

Aoi Satoh

4

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9 April 2020

Fusaka Oikawa

5

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9 April 2020

Hiroshi Ohno

6

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9 April 2020

Yoshinori Osaki

7

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9 April 2020

Takashi Matsuzaka

8

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9 April 2020

Motohiro Sekiya

9

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9 April 2020

Hitoshi Iwasaki

10

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9 April 2020

Shigeru Yatoh

11

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9 April 2020

Hiroaki Suzuki

13

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9 April 2020

Nobuhiro Yamada

14

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9 April 2020

Yoshimi Nakagawa

15

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9 April 2020

Hitoshi Shimano

16

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9 April 2020

publication date

25 April 2017

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9 April 2020

Journal of Diabetes Investigation

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9 April 2020

8

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9 April 2020

446-452

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9 April 2020

4

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9 April 2020

Selective peroxisome proliferator-activated receptor α modulators (SPPARMα): the next generation of peroxisome proliferator-activated receptor α-agonists

1 reference

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9 September 2017

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

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9 September 2017

Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner

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9 September 2017

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

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9 September 2017

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

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9 September 2017

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.

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9 September 2017

Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease

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9 September 2017

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group

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9 September 2017

TFE3 controls lipid metabolism in adipose tissue of male mice by suppressing lipolysis and thermogenesis

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17 June 2018

TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes

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17 June 2018

Transcriptome Analysis of K-877 (a Novel Selective PPARα Modulator (SPPARMα))-Regulated Genes in Primary Human Hepatocytes and the Mouse Liver.

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21 August 2018

Central role of PPARalpha-dependent hepatic lipid turnover in dietary steatohepatitis in mice

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21 August 2018

Blood lipids and first-ever ischemic stroke/transient ischemic attack in the Bezafibrate Infarction Prevention (BIP) Registry: high triglycerides constitute an independent risk factor

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21 August 2018

Reduction in stroke with gemfibrozil in men with coronary heart disease and low HDL cholesterol: The Veterans Affairs HDL Intervention Trial (VA-HIT).

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21 August 2018

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis

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21 January 2018

Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia

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21 January 2018

Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study

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12 December 2020

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Identifiers

10.1111/JDI.12621

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084058%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference

Europe PubMed Central

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9 April 2020

1 reference

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9 April 2020

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