SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes. (Q34289658)

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17 November 2019

title

SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes (English)

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17 November 2019

5

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17 November 2019

Hirohito Sone

10

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17 November 2019

2

Hitoshi Shimano

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17 November 2019

6

Takashi Matsuzaka

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17 November 2019

3

Yoshimi Nakagawa

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17 November 2019

8

Akimitsu Takahashi

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17 November 2019

11

Hideo Toyoshima

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17 November 2019

4

Tomohiro Ide

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17 November 2019

7

Masanori Nakakuki

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17 November 2019

author name string

Takashi Yamamoto

1

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17 November 2019

Hiroaki Suzuki

9

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17 November 2019

Ryuichiro Sato

12

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17 November 2019

Nobuhiro Yamada

13

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language of work or name

English

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publication date

13 January 2004

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Journal of Biological Chemistry

17 November 2019

published in

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17 November 2019

volume

279

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17 November 2019

page(s)

12027-12035

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issue

13

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Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression

17 November 2019

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Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes

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The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

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Polyunsaturated fatty acyl coenzyme A suppress the glucose-6-phosphatase promoter activity by modulating the DNA binding of hepatocyte nuclear factor 4 alpha.

21 January 2018

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Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

21 January 2018

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Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

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The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

21 January 2018

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Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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Sterol regulatory element-binding protein-1 as a dominant transcription factor for gene regulation of lipogenic enzymes in the liver

21 January 2018

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Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

21 January 2018

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Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism

21 January 2018

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

21 January 2018

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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

21 January 2018

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Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

21 January 2018

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Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

21 January 2018

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Crystal structure of the HNF4 alpha ligand binding domain in complex with endogenous fatty acid ligand

21 January 2018

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Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

21 January 2018

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Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

21 January 2018

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Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

21 January 2018

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Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

21 January 2018

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Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level.

21 January 2018

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Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

21 January 2018

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Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

21 January 2018

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Organization and partial sequence of the hepatocyte nuclear factor-4 alpha/MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY

21 January 2018

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A missense mutation in hepatocyte nuclear factor-4 alpha, resulting in a reduced transactivation activity, in human late-onset non-insulin-dependent diabetes mellitus

21 January 2018

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Sterol regulatory element-binding protein-2 interacts with hepatocyte nuclear factor-4 to enhance sterol isomerase gene expression in hepatocytes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310333200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14722127%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference