Nucleic acid-sensing TLRs: trafficking and regulation. (Q39025992)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

review article

1 reference

title

Nucleic acid-sensing TLRs: trafficking and regulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

0 references

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

author name string

Olivia Majer

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

Bo Liu

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

publication date

28 November 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

Current Opinion in Immunology

28 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

volume

44

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28 March 2020

page(s)

26-33

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Discriminating self from non-self in nucleic acid sensing

28 March 2020

cites work

1 reference

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Emerging roles of the processing of nucleic acids and Toll-like receptors in innate immune responses to nucleic acids

17 June 2018

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Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

17 June 2018

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TLR9 stability and signaling are regulated by phosphorylation and cell stress.

17 June 2018

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Autoinhibition and relief mechanism by the proteolytic processing of Toll-like receptor 8.

17 June 2018

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Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9

17 June 2018

1 reference

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Guanosine and its modified derivatives are endogenous ligands for TLR7.

17 June 2018

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LRRC59 Regulates Trafficking of Nucleic Acid-Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1.

17 June 2018

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Regulation of TLR3 Activation by S100A9.

17 June 2018

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ADP-Ribosylation Factor 3 Mediates Cytidine-Phosphate-Guanosine Oligodeoxynucleotide-Induced Responses by Regulating Toll-Like Receptor 9 Trafficking.

17 June 2018

1 reference

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Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

17 June 2018

1 reference

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Synergistic activation of Toll-like receptor 8 by two RNA degradation products.

17 June 2018

1 reference

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Toll-like receptor 8 senses degradation products of single-stranded RNA

17 June 2018

1 reference

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Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice

17 June 2018

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Endosomal localization of TLR8 confers distinctive proteolytic processing on human myeloid cells

17 June 2018

1 reference

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DNase γ is the effector endonuclease for internucleosomal DNA fragmentation in necrosis

17 June 2018

1 reference

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Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes

17 June 2018

1 reference

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Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

17 June 2018

1 reference

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Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing

17 June 2018

1 reference

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UNC93B1 mediates differential trafficking of endosomal TLRs

17 June 2018

1 reference

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Cleaved/associated TLR3 represents the primary form of the signaling receptor

17 June 2018

1 reference

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STING manifests self DNA-dependent inflammatory disease

17 June 2018

1 reference

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Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Cofactors required for TLR7- and TLR9-dependent innate immune responses

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Accessory molecules for Toll-like receptors and their function

17 June 2018

1 reference

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Cutting edge: a TLR9 cytoplasmic tyrosine motif is selectively required for proinflammatory cytokine production

17 June 2018

1 reference

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Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

17 June 2018

1 reference

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Nucleic acid sensing Toll-like receptors in autoimmunity

17 June 2018

1 reference

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Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone

17 June 2018

1 reference

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Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3

17 June 2018

1 reference

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The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

17 June 2018

1 reference

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TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

17 June 2018

1 reference

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Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

17 June 2018

1 reference

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Structural Basis of Toll-Like Receptor 3 Signaling with Double-Stranded RNA

17 June 2018

1 reference

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

17 June 2018

1 reference

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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.

17 June 2018

1 reference

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Herpes simplex virus encephalitis in human UNC-93B deficiency

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5446938

Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication

17 June 2018

1 reference

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Crystal structure of human toll-like receptor 3 (TLR3) ectodomain

17 June 2018

1 reference

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

17 June 2018

1 reference

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Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

17 June 2018

1 reference

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TLR9 signals after translocating from the ER to CpG DNA in the lysosome

17 June 2018

1 reference

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Deoxyribonuclease I-like III is an inducible macrophage barrier to liposomal transfection

17 June 2018

1 reference

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Mutation of DNASE1 in people with systemic lupus erythematosus

17 June 2018

1 reference

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Features of systemic lupus erythematosus in Dnase1-deficient mice

17 June 2018

1 reference

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Approaching the asymptote? Evolution and revolution in immunology

17 June 2018

1 reference

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Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

17 June 2018

1 reference

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Complex Negative Regulation of TLR9 by Multiple Proteolytic Cleavage Events

21 August 2018

1 reference

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Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands

21 August 2018

1 reference

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An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

21 August 2018

1 reference

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Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

21 August 2018

1 reference

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Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells

21 August 2018

1 reference

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Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

21 August 2018

1 reference

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Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities.

21 August 2018

1 reference

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Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27907816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNase II-dependent DNA digestion is required for DNA sensing by TLR9

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27907816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.COI.2016.10.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27907816%20AND%20SRC:MED&resulttype=core&format=json

28 March 2020

1 reference