Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms (Q39033323)

8 September 2017

title

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms (English)

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8 September 2017

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28

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Martina Müller-Nurasyid

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Martina Müller-Nurasyid

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Harald Grallert

4

Harald Grallert

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8 September 2017

Simon N Dankel

2

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Joao Fadista

Joao Fadista

9

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Helmut Laumen

Helmut Laumen

38

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Thomas Skurk

Thomas Skurk

19

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Ingrid Dahlman

Ingrid Dahlman

27

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Karsten Suhre

Karsten Suhre

34

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Stefanie M. Hauck

Stefanie M Hauck

29

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Matthias Blüher

30

Matthias Blüher

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8 September 2017

Tina Rönn

14

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Thomas Illig

33

Thomas Illig

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32

Leif Groop

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31

Peter Arner

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36

Gunnar Mellgren

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1

Melina Claussnitzer

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5

Viktoria Glunk

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11

Simone Wahl

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Hans Hauner

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Bernward Klocke

3

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Tea Berulava

6

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Heekyoung Lee

7

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Nikolay Oskolkov

8

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Kerstin Ehlers

10

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Christoph Hoffmann

12

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Kun Qian

13

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Helene Riess

15

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Nancy Bretschneider

17

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Timm Schroeder

18

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Bernhard Horsthemke

20

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DIAGRAM+Consortium

21

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8 September 2017

Derek Spieler

22

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Martin Seifert

24

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Michael J Kern

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Niklas Mejhert

26

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Yi-Hsiang Hsu

35

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8 September 2017

language of work or name

English

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publication date

1 January 2014

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8 September 2017

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8 September 2017

volume

156

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8 September 2017

issue

1-2

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8 September 2017

page(s)

343-358

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Phosphoenolpyruvate carboxykinase and the synthesis of glyceride-glycerol from pyruvate in adipose tissue.

8 September 2017

cites work

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12 December 2020

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

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12 December 2020

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

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12 December 2020

The hardwiring of development: organization and function of genomic regulatory systems.

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12 December 2020

A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

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12 December 2020

PPARgamma3 mRNA: a distinct PPARgamma mRNA subtype transcribed from an independent promoter

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12 December 2020

PPARγ Is Required for the Differentiation of Adipose Tissue In Vivo and In Vitro

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12 December 2020

Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young

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12 December 2020

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

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12 December 2020

Initial sequencing and comparative analysis of the mouse genome

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12 December 2020

Clustering of DNA sequences in human promoters

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12 December 2020

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

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12 December 2020

Effects of Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma2 gene on rosiglitazone response in type 2 diabetes

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12 December 2020

Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.

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12 December 2020

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population

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12 December 2020

In vivo enhancer analysis of human conserved non-coding sequences

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12 December 2020

Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.

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12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

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12 December 2020

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

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12 December 2020

An illustrated review of early pancreas development in the mouse.

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12 December 2020

The emerging genetic architecture of type 2 diabetes

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12 December 2020

Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data

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12 December 2020

The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface

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12 December 2020

ChIP-seq accurately predicts tissue-specific activity of enhancers

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12 December 2020

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

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12 December 2020

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer

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12 December 2020

Genomic views of distant-acting enhancers

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12 December 2020

Combinatorial binding predicts spatio-temporal cis-regulatory activity

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12 December 2020

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

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12 December 2020

Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice

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12 December 2020

Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations

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12 December 2020

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

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12 December 2020

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

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12 December 2020

ChIP-Seq identification of weakly conserved heart enhancers

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12 December 2020

A High-Frequency Regulatory Polymorphism in the p53 Pathway Accelerates Tumor Development

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12 December 2020

A large-scale, consortium-based genomewide association study of asthma

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12 December 2020

Comparative Epigenomic Analysis of Murine and Human Adipogenesis

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12 December 2020

Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci

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12 December 2020

A user's guide to the encyclopedia of DNA elements (ENCODE)

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12 December 2020

An intronic SNP in the thyroid hormone receptor β gene is associated with pituitary cell-specific over-expression of a mutant thyroid hormone receptor β2 (R338W) in the index case of pituitary-selective resistance to thyroid hormone

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12 December 2020

A high-resolution map of human evolutionary constraint using 29 mammals

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12 December 2020

A transcription factor collective defines cardiac cell fate and reflects lineage history

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12 December 2020

Leveraging models of cell regulation and GWAS data in integrative network-based association studies

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12 December 2020

An integrated encyclopedia of DNA elements in the human genome

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12 December 2020

Systematic localization of common disease-associated variation in regulatory DNA

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12 December 2020

Linking disease associations with regulatory information in the human genome

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12 December 2020

Evidence of abundant purifying selection in humans for recently acquired regulatory functions

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12 December 2020

Bayesian refinement of association signals for 14 loci in 3 common diseases

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12 December 2020

An integrated map of genetic variation from 1,092 human genomes

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12 December 2020

Interpreting noncoding genetic variation in complex traits and human disease

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12 December 2020

The transcription factor paired-related homeobox 1 (Prrx1) inhibits adipogenesis by activating transforming growth factor-β (TGFβ) signaling

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12 December 2020

A high-resolution enhancer atlas of the developing telencephalon

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12 December 2020

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

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12 December 2020

10.1016/J.CELL.2013.10.058

Identifiers

DOI

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8 September 2017

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