Senescent cells harbour features of the cancer epigenome. (Q39056256)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Senescent cells harbour features of the cancer epigenome (English)

1 reference

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1 March 2020

12

1 reference

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1 March 2020

Joanne Edwards

13

1 reference

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1 March 2020

Shelley L. Berger

14

1 reference

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1 March 2020

author name string

Hazel A Cruickshanks

1

1 reference

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1 March 2020

Tony McBryan

2

1 reference

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1 March 2020

David M Nelson

3

1 reference

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1 March 2020

Nathan D Vanderkraats

4

1 reference

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1 March 2020

Parisha P Shah

5

1 reference

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1 March 2020

John van Tuyn

6

1 reference

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1 March 2020

Taranjit Singh Rai

7

1 reference

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1 March 2020

Claire Brock

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Greg Donahue

9

1 reference

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1 March 2020

Donncha S Dunican

10

1 reference

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1 March 2020

Mark E Drotar

11

1 reference

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1 March 2020

Peter D Adams

15

1 reference

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1 March 2020

publication date

24 November 2013

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

15

1 reference

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1 March 2020

page(s)

1495-1506

1 reference

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1 March 2020

issue

12

1 reference

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describes a project that uses

1 March 2020

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=4106249

exact match

https://scigraph.springernature.com/pub.10.1038/ncb2879

0 references

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9 September 2017

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9 September 2017

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9 September 2017

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Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks

9 September 2017

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Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis

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Comparative analysis of DNA replication timing reveals conserved large-scale chromosomal architecture.

9 September 2017

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The senescence-associated secretory phenotype: the dark side of tumor suppression

9 September 2017

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Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

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9 September 2017

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9 September 2017

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DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer

9 September 2017

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9 September 2017

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The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

9 September 2017

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9 September 2017

1 reference

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Short telomeres limit tumor progression in vivo by inducing senescence

9 September 2017

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9 September 2017

1 reference

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

9 September 2017

1 reference

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The epigenetic progenitor origin of human cancer

9 September 2017

1 reference

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

9 September 2017

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

9 September 2017

1 reference

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Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

9 September 2017

1 reference

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Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

9 September 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

9 September 2017

1 reference

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Induction of Tumors in Mice by Genomic Hypomethylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

CpG island methylator phenotype in colorectal cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Transcription of IAP endogenous retroviruses is constrained by cytosine methylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

DNA methyltransferase 1 knockdown activates a replication stress checkpoint.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Replication timing-related and gene body-specific methylation of active human genes.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Human chromosome 1 satellite 3 DNA is decondensed, demethylated and transcribed in senescent cells and in A431 epithelial carcinoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Developmental differences in the immortalization of lung fibroblasts by telomerase

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Telomerase expression in normal human fibroblasts stabilizes DNA 5-methylcytosine transferase I.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Increased methylation variation in epigenetic domains across cancer types

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation of p16INK4a

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Cellular senescence in aging primates.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Oncogene-induced senescence as an initial barrier in lymphoma development

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106249

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCB2879

Comparison of global DNA methylation profiles in replicative versus premature senescence

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24270890

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24270890

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

DNA methylation decreases in aging but not in immortal cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24270890

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCB2879

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24270890%20AND%20SRC:MED&resulttype=core&format=json