Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi. (Q39075901)

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28 February 2020

title

Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi (English)

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28 February 2020

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12

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16

Jean-Robert Ioset

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28 February 2020

author name string

Martine Keenan

1

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28 February 2020

Paul W Alexander

2

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28 February 2020

Jason H Chaplin

3

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28 February 2020

Michael J Abbott

4

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28 February 2020

Hugo Diao

5

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28 February 2020

Zhisen Wang

6

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28 February 2020

Wayne M Best

7

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Catherine J Perez

8

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Scott M J Cornwall

9

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28 February 2020

Sarah K Keatley

10

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28 February 2020

R C Andrew Thompson

11

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Karen L White

13

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Eileen Ryan

14

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Gong Chen

15

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28 February 2020

Thomas W von Geldern

17

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Eric Chatelain

18

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28 February 2020

publication date

1 October 2013

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Future Medicinal Chemistry

28 February 2020

published in

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volume

5

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28 February 2020

issue

15

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28 February 2020

page(s)

1733-1752

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Chagas disease has now gone global

28 February 2020

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In vitro and in vivo activities of ravuconazole on Trypanosoma cruzi, the causative agent of Chagas disease

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Chemotherapy with benznidazole and itraconazole for mice infected with different Trypanosoma cruzi clonal genotypes

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Parasitological cure of acute and chronic experimental Chagas disease using the long-acting experimental triazole TAK-187. Activity against drug-resistant Trypanosoma cruzi strains

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Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population

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21 January 2018

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Unequivocal identification of subpopulations in putative multiclonal Trypanosoma cruzi strains by FACs single cell sorting and genotyping

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Trypanosoma cruzi isolates from Chile are heterogeneous and composed of mixed populations when characterized by schizodeme and Southern analyses.

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Discovery of a Novel Class of Orally Active Trypanocidal N -Myristoyltransferase Inhibitors

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Identifiers

DOI

10.4155/FMC.13.139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24144410%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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