Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR. (Q39079755)

8 September 2017

Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR. (English)

1 reference

8 September 2017

protein ubiquitination

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Stanimir S Ivanov

1

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Craig R. Roy

object named as

Craig R Roy

series ordinal

2

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language of work or name

English

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publication date

13 October 2013

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8 September 2017

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8 September 2017

14

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8 September 2017

12

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8 September 2017

1219-1228

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describes a project that uses

8 September 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3839319/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ni.2740

0 references

cites work

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

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From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines

9 September 2017

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The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

9 September 2017

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mTOR signaling in growth control and disease

9 September 2017

1 reference

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The protein SdhA maintains the integrity of the Legionella-containing vacuole

9 September 2017

1 reference

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Signaling in innate immunity and inflammation

9 September 2017

1 reference

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The role of ubiquitylation in immune defence and pathogen evasion

9 September 2017

1 reference

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Regulation of immune responses by mTOR.

9 September 2017

1 reference

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Return to homeostasis: downregulation of NF-κB responses

9 September 2017

1 reference

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Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila.

9 September 2017

1 reference

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How cells deploy ubiquitin and autophagy to defend their cytosol from bacterial invasion

9 September 2017

1 reference

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Modulation of host cell function by Legionella pneumophila type IV effectors

9 September 2017

1 reference

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Decoding signalling networks by mass spectrometry-based proteomics

9 September 2017

1 reference

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Immunology taught by bacteria

9 September 2017

1 reference

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Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila

9 September 2017

1 reference

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The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

9 September 2017

1 reference

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The E3 ligase TRAF6 regulates Akt ubiquitination and activation

9 September 2017

1 reference

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Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system

9 September 2017

1 reference

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

9 September 2017

1 reference

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System-wide changes to SUMO modifications in response to heat shock

9 September 2017

1 reference

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila

9 September 2017

1 reference

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The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

9 September 2017

1 reference

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Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

The Legionella pneumophila IcmSW complex interacts with multiple Dot/Icm effectors to facilitate type IV translocation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Post-transcriptional regulation of proinflammatory proteins.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Role of translocation in the activation and function of protein kinase B

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Modulation of ubiquitin dynamics and suppression of DALIS formation by the Legionella pneumophila Dot/Icm system

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Delivery of protein to the cytosol of macrophages using Escherichia coli K-12.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

The phosphoproteome of toll-like receptor-activated macrophages

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Infection-induced host translational blockage inhibits immune responses and epithelial renewal in the Drosophila gut.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

SUnSET, a nonradioactive method to monitor protein synthesis.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

The TSC-mTOR signaling pathway regulates the innate inflammatory response

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3839319

Translational control of the innate immune response through IRF-7

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.2740

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth

21 January 2018

1 reference

12 December 2020

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

12 December 2020

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1 reference

12 December 2020

The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection

1 reference

12 December 2020

Type I interferons as anti-inflammatory mediators

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.2740

1 reference

Dimensions Publication ID

8 September 2017

1014648535

0 references

Fatcat ID

release_yranjyywwng6xfaxnzsgojdz2u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/yranjyywwng6xfaxnzsgojdz2u

24 November 2022

mapped directly with Wikidata item

1 reference

8 September 2017

1 reference