WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells (Q39144973)

9 September 2017

WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells (English)

1 reference

Shivendra Kumar Chaurasiya

9 September 2017

Chandra Prakash Prasad

series ordinal

1

0 references

Tommy Andersson

object named as

Tommy Andersson

series ordinal

4

0 references

series ordinal

2

object named as

Shivendra Kumar Chaurasiya

1 reference

9 September 2017

3

Lena Axelsson

1 reference

9 September 2017

28 April 2013

1 reference

9 September 2017

1 reference

9 September 2017

7

1 reference

9 September 2017

5

1 reference

9 September 2017

870-883

1 reference

PMCID

5528454

describes a project that uses

9 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5528454/fullTextXML

inferred from PubMed Central ID database lookup

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Signal transduction by the Wnt family of ligands

10 September 2017

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10 September 2017

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Molecular cloning of the human proto-oncogene Wnt-5A and mapping of the gene (WNT5A) to chromosome 3p14-p21

10 September 2017

1 reference

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Differential transformation of mammary epithelial cells by Wnt genes

10 September 2017

1 reference

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ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.

10 September 2017

1 reference

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Cdc42 negatively regulates intrinsic migration of highly aggressive breast cancer cells

10 September 2017

1 reference

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Raf-MEK-Erk cascade in anoikis is controlled by Rac1 and Cdc42 via Akt.

10 September 2017

1 reference

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Determination of ERK activity: anti-phospho-ERK antibodies and in vitro phosphorylation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

WNT5A expression increases during melanoma progression and correlates with outcome

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

WNT5A exhibits tumor-suppressive activity through antagonizing the Wnt/beta-catenin signaling, and is frequently methylated in colorectal cancer.

14 September 2017

1 reference

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WNT5A, a putative tumour suppressor of lymphoid malignancies, is inactivated by aberrant methylation in acute lymphoblastic leukaemia

14 September 2017

1 reference

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Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.

14 September 2017

1 reference

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A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells

14 September 2017

1 reference

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Wnt-5a protein expression in primary dukes B colon cancers identifies a subgroup of patients with good prognosis

14 September 2017

1 reference

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Repression of Wnt-5a impairs DDR1 phosphorylation and modifies adhesion and migration of mammary cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Transformation by Wnt family proteins correlates with regulation of beta-catenin

25 September 2017

1 reference

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Reversion of uroepithelial cell tumorigenesis by the ectopic expression of human wnt-5a

25 September 2017

1 reference

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Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Regulated expression of Wnt family members during proliferation of C57mg mammary cells

15 June 2018

1 reference

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Activation of MAP kinases by calcium-dependent and calcium-independent pathways. Stimulation by thapsigargin and epidermal growth factor

15 June 2018

1 reference

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The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Regulation of homocysteine-induced MMP-9 by ERK1/2 pathway

21 August 2018

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Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: the role of ERK1/2, PI3K, and matrix metalloproteinases

21 August 2018

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Testosterone stimulates intracellular calcium release and mitogen-activated protein kinases via a G protein-coupled receptor in skeletal muscle cells

21 August 2018

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Wnt-5a and G-protein signaling are required for collagen-induced DDR1 receptor activation and normal mammary cell adhesion

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Rho GTPases are over-expressed in human tumors.

21 August 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5528454

Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion

21 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23727359

12 December 2020

inferred from PubMed ID database lookup

Expression of Wnt-5a and its clinicopathological significance in hepatocellular carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23727359

12 December 2020

inferred from PubMed ID database lookup

Rho GTPase CDC42 regulates directionality and random movement via distinct MAPK pathways in neutrophils

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23727359

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MOLONC.2013.04.005

1 reference

9 September 2017

1 reference

9 September 2017

1 reference

PMCID

5528454