Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla (Q39207497)

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scientific article published on 14 November 2012

Language	Label	Description	Also known as
English	Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla	scientific article published on 14 November 2012

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scholarly article

1 reference

Europe PubMed Central

10 September 2017

Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla (English)

1 reference

Europe PubMed Central

10 September 2017

Josef Penninger

6

1 reference

Europe PubMed Central

10 September 2017

Guillaume E Desanti

object named as

Guillaume E Desanti

1

0 references

William E. Jenkinson

object named as

William E Jenkinson

9

0 references

Graham Anderson

object named as

Graham Anderson

10

0 references

author name string

Jennifer E Cowan

2

1 reference

Europe PubMed Central

10 September 2017

Song Baik

3

1 reference

Europe PubMed Central

10 September 2017

Sonia M Parnell

4

1 reference

Europe PubMed Central

10 September 2017

Andrea J White

5

1 reference

Europe PubMed Central

10 September 2017

Peter J L Lane

7

1 reference

Europe PubMed Central

10 September 2017

Eric J Jenkinson

8

1 reference

Europe PubMed Central

10 September 2017

language of work or name

0 references

publication date

14 November 2012

1 reference

Europe PubMed Central

10 September 2017

Journal of Immunology

1 reference

Europe PubMed Central

10 September 2017

189

1 reference

Europe PubMed Central

10 September 2017

12

1 reference

Europe PubMed Central

10 September 2017

5519-5526

1 reference

Europe PubMed Central

10 September 2017

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Control of central self-tolerance induction by autoreactive CD4+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Thymic emigration revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Regulation of CD8+ T cell development by thymus-specific proteasomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

The thymus as an inductive site for T lymphopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Spontaneous autoimmunity prevented by thymic expression of a single self-antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Journey through the thymus: stromal guides for T-cell development and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

New member of the winged-helix protein family disrupted in mouse and rat nude mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Humoral immune responses in CD40 ligand-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

10 September 2017

Reaggregate thymus cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

14 September 2017

Preparation of 2-dGuo-treated thymus organ cultures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

14 September 2017

Transfection and ligation of CD40 in human oral keratinocytes affect proliferation, adhesion and migration but not apoptosis in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

14 September 2017

Thymus medulla consisting of epithelial islets each derived from a single progenitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

25 September 2017

The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

Delta-like 4 is indispensable in thymic environment specific for T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

CD40 ligation alters the cell cycle of differentiating keratinocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

Growth of epithelial cells in the thymic medulla is under the control of mature T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

17 June 2018

Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Continued maturation of thymic emigrants in the periphery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

Thymic overexpression of CD40 ligand disrupts normal thymic epithelial organization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3605790

21 August 2018

The impact of cell re-entry into the primary lymphoid organs on lymphocyte repertoire and functionality

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Checkpoints in the development of thymic cortical epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23152561

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1201815

1 reference

Europe PubMed Central

10 September 2017

1 reference

Europe PubMed Central

10 September 2017

1 reference

Europe PubMed Central

10 September 2017

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