Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma. (Q39218915)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23274910%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma (English)

1 reference

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21 February 2020

4

1 reference

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21 February 2020

Ultan McDermott

7

1 reference

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21 February 2020

10

Leif W Ellisen

1 reference

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21 February 2020

5

Patricia Greninger

1 reference

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21 February 2020

author name string

Lei He

1

1 reference

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21 February 2020

Kristine Torres-Lockhart

2

1 reference

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21 February 2020

Nicole Forster

3

1 reference

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21 February 2020

Mathew J Garnett

6

1 reference

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21 February 2020

Stephen M Rothenberg

8

1 reference

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21 February 2020

Cyril H Benes

9

1 reference

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21 February 2020

publication date

28 December 2012

1 reference

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21 February 2020

1 reference

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21 February 2020

volume

3

1 reference

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21 February 2020

page(s)

324-337

1 reference

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21 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23274910%20AND%20SRC:MED&resulttype=core&format=json

The molecular pathogenesis of head and neck squamous cell carcinoma

21 February 2020

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10 September 2017

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

10 September 2017

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Phase I study of Navitoclax (ABT-263), a novel Bcl-2 family inhibitor, in patients with small-cell lung cancer and other solid tumors

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The molecular biology of head and neck cancer

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The landscape of somatic copy-number alteration across human cancers

10 September 2017

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The BCL-2 family reunion

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Drug combination studies and their synergy quantification using the Chou-Talalay method

10 September 2017

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BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists

10 September 2017

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10 September 2017

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Bim upregulation by histone deacetylase inhibitors mediates interactions with the Bcl-2 antagonist ABT-737: evidence for distinct roles for Bcl-2, Bcl-xL, and Mcl-1.

10 September 2017

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10 September 2017

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

10 September 2017

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Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma

10 September 2017

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14 September 2017

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14 September 2017

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Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer

14 September 2017

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A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunity

14 September 2017

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ABT-737 synergizes with chemotherapy to kill head and neck squamous cell carcinoma cells via a Noxa-mediated pathway

14 September 2017

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

14 September 2017

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Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

14 September 2017

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bcl-2 protein expression correlates with recurrence and survival in early stage head and neck cancer treated by radiotherapy

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23274910

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-12-0417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23274910%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23274910%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23274910%20AND%20SRC:MED&resulttype=core&format=json