The Na+ /H+ -exchanger (NHE1) generates pH nanodomains at focal adhesions (Q39237799)

10 September 2017

title

The Na+ /H+ -exchanger (NHE1) generates pH nanodomains at focal adhesions (English)

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10 September 2017

Florian Timo Ludwig

1

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10 September 2017

Albrecht Schwab

series ordinal

2

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10 September 2017

Christian Stock

series ordinal

3

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10 September 2017

publication date

1 June 2013

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Journal of Cellular Physiology

10 September 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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10 September 2017

volume

228

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10 September 2017

issue

6

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10 September 2017

page(s)

1351-1358

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Cell-substrate contacts illuminated by total internal reflection fluorescence

10 September 2017

cites work

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Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

21 January 2018

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Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1.

21 January 2018

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Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

21 January 2018

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The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site

21 January 2018

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Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding

21 January 2018

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Mechanical integration of actin and adhesion dynamics in cell migration

21 January 2018

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Protons and Ca2+: ionic allies in tumor progression?

21 January 2018

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Potentiation of TRPM7 inward currents by protons

21 January 2018

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Nanoscale architecture of integrin-based cell adhesions

21 January 2018

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Otto Warburg's contributions to current concepts of cancer metabolism

21 January 2018

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The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrin-mediated migration of human melanoma cells.

21 January 2018

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A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens

21 January 2018

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The Na+/H+ exchanger NHE1, but not the Na+, HCO3(-) cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2.

21 January 2018

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NHE1 mediates MDA-MB-231 cells invasion through the regulation of MT1-MMP.

21 January 2018

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Functional hierarchy of simultaneously expressed adhesion receptors: integrin alpha2beta1 but not CD44 mediates MV3 melanoma cell migration and matrix reorganization within three-dimensional hyaluronan-containing collagen matrices

21 January 2018

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Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

21 January 2018

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Coronin 2A regulates a subset of focal-adhesion-turnover events through the cofilin pathway

21 January 2018

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Intracellular pH gradients in migrating cells

21 January 2018

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Acidic extracellular pH promotes activation of integrin α(v)β(3).

21 January 2018

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Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex

21 January 2018

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Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

21 January 2018

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Cell migration: integrating signals from front to back

21 January 2018

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Potentiation of TRPC5 by protons

21 January 2018

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Intracellular pH sensors: design principles and functional significance

21 January 2018

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Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling

21 January 2018

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Protons extruded by NHE1: digestive or glue?

21 January 2018

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Migration of human melanoma cells depends on extracellular pH and Na+/H+ exchange

21 January 2018

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Is the multifunctional Na(+)/H(+) exchanger isoform 1 a potential therapeutic target in cancer?

21 January 2018

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pH nanoenvironment at the surface of single melanoma cells

21 January 2018

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Protons make tumor cells move like clockwork

21 January 2018

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pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution

21 January 2018

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Invasive matrix degradation at focal adhesions occurs via protease recruitment by a FAK-p130Cas complex

21 January 2018

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Dysregulated pH: a perfect storm for cancer progression.

21 January 2018

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FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

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Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again

21 January 2018

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Extracellular pH determines the rate of Ca2+ entry into Madin-Darby canine kidney-focus cells

21 January 2018

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Modifier role of internal H+ in activating the Na+–H+ exchanger in renal microvillus membrane vesicles

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24293

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10 September 2017

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