Perifosine induces cell apoptosis in human osteosarcoma cells: new implication for osteosarcoma therapy? (Q39270813)

10 September 2017

title

Perifosine induces cell apoptosis in human osteosarcoma cells: new implication for osteosarcoma therapy? (English)

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10 September 2017

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Chen Yao

1

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10 September 2017

Jian-jun Wei

2

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10 September 2017

Zu-yu Wang

3

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10 September 2017

Hui-min Ding

4

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10 September 2017

Dong Li

5

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10 September 2017

Shi-chang Yan

6

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10 September 2017

Yong-jiang Yang

7

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10 September 2017

Zhang-ping Gu

8

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10 September 2017

publication date

1 March 2013

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Cell Biochemistry and Biophysics

10 September 2017

published in

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10 September 2017

volume

65

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10 September 2017

issue

2

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10 September 2017

page(s)

217-227

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Historical, current and future aspects of osteosarcoma treatment

10 September 2017

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The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism

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Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species

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Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells

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Perifosine, an oral bioactive novel alkylphospholipid, inhibits Akt and induces in vitro and in vivo cytotoxicity in human multiple myeloma cells

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Combination treatment of prostate cancer cell lines with bioactive soy isoflavones and perifosine causes increased growth arrest and/or apoptosis

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Alkyl-lysophospholipids as anticancer agents and enhancers of radiation-induced apoptosis

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21 January 2018

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10.1007/S12013-012-9423-5

21 January 2018

Identifiers

DOI

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10 September 2017

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