LEDGF (p75) promotes DNA-end resection and homologous recombination (Q39318006)

11 September 2017

LEDGF (p75) promotes DNA-end resection and homologous recombination (English)

1 reference

11 September 2017

10

Jiri Bartek

0 references

Jiří Lukáš

11

Jiri Lukas

0 references

Kasper Fugger

Kasper Fugger

3

0 references

Mads Daugaard

Mads Daugaard

1

0 references

Claudia Lukas

Claudia Lukas

9

0 references

author name string

Annika Baude

2

1 reference

11 September 2017

Lou Klitgaard Povlsen

4

1 reference

11 September 2017

Halfdan Beck

5

1 reference

11 September 2017

Claus Storgaard Sørensen

6

1 reference

11 September 2017

Nikolaj H T Petersen

7

1 reference

11 September 2017

Poul H B Sorensen

8

1 reference

11 September 2017

Mikkel Rohde

12

1 reference

11 September 2017

Marja Jäättelä

13

1 reference

11 September 2017

8 July 2012

1 reference

Nature Structural & Molecular Biology

11 September 2017

1 reference

11 September 2017

19

1 reference

11 September 2017

8

1 reference

11 September 2017

803-810

1 reference

https://scigraph.springernature.com/pub.10.1038/nsmb.2314

11 September 2017

0 references

cites work

Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.

1 reference

A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2

21 January 2018

1 reference

Alternative splicing and caspase-mediated cleavage generate antagonistic variants of the stress oncoprotein LEDGF/p75.

21 January 2018

1 reference

Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus

21 January 2018

1 reference

The family of hepatoma-derived growth factor proteins: characterization of a new member HRP-4 and classification of its subfamilies

21 January 2018

1 reference

Disruption of Ledgf/Psip1 results in perinatal mortality and homeotic skeletal transformations

21 January 2018

1 reference

Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ.

21 January 2018

1 reference

Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity

21 January 2018

1 reference

Transcriptional co-activator p75 binds and tethers the Myc-interacting protein JPO2 to chromatin

21 January 2018

1 reference

Menin critically links MLL proteins with LEDGF on cancer-associated target genes

21 January 2018

1 reference

A role for LEDGF/p75 in targeting HIV DNA integration

21 January 2018

1 reference

Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

21 January 2018

1 reference

Mechanisms governing lentivirus integration site selection

21 January 2018

1 reference

High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region

21 January 2018

1 reference

Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor

21 January 2018

1 reference

Lens epithelium-derived growth factor/p75 qualifies as a target for HIV gene therapy in the NSG mouse model.

21 January 2018

1 reference

Inhibition of the interaction between HIV-1 integrase and its cofactor LEDGF/p75: a promising approach in anti-retroviral therapy

21 January 2018

1 reference

Fusion of the NUP98 gene with the LEDGF/p52 gene defines a recurrent acute myeloid leukemia translocation

21 January 2018

1 reference

Antinuclear autoantibodies in prostate cancer: immunity to LEDGF/p75, a survival protein highly expressed in prostate tumors and cleaved during apoptosis

21 January 2018

1 reference

Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein

21 January 2018

1 reference

Human mismatch repair protein MSH6 contains a PWWP domain that targets double stranded DNA.

21 January 2018

1 reference

Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1

21 January 2018

1 reference

Human CtIP promotes DNA end resection

21 January 2018

1 reference

DNA repair in response to anthracycline-DNA adducts: a role for both homologous recombination and nucleotide excision repair.

21 January 2018

1 reference

The DNA-damage response in human biology and disease

21 January 2018

1 reference

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

21 January 2018

1 reference

DNA resection in eukaryotes: deciding how to fix the break

21 January 2018

1 reference

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

21 January 2018

1 reference

At loose ends: resecting a double-strand break

21 January 2018

1 reference

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

21 January 2018

1 reference

Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes

21 January 2018

1 reference

NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse

21 January 2018

1 reference

CtIP links DNA double-strand break sensing to resection

21 January 2018

1 reference

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

21 January 2018

1 reference

Solution structure of the HIV-1 integrase-binding domain in LEDGF/p75

21 January 2018

1 reference

Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1

21 January 2018

1 reference

The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation

21 January 2018

1 reference

Breaking barriers to transcription elongation

21 January 2018

1 reference

CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression

21 January 2018

1 reference

Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair

21 January 2018

1 reference

Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency

21 January 2018

1 reference

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 January 2018

1 reference

Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice

21 January 2018

1 reference

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers

21 January 2018

1 reference

Retroviral DNA integration and the DNA damage response

21 January 2018

1 reference

Effects of cell cycle status on early events in retroviral replication

21 January 2018

1 reference

DNA-damage response pathways triggered by viral replication.

21 January 2018

1 reference

Topoisomerase I inhibitors: camptothecins and beyond

21 January 2018

1 reference

Break-induced replication: what is it and what is it for?

21 January 2018

1 reference

Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase.

21 January 2018

1 reference

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

21 January 2018

1 reference

Lens Epithelium-Derived Growth Factor Is an Hsp70-2 Regulated Guardian of Lysosomal Stability in Human Cancer

21 January 2018

1 reference

Single-strand break repair and genetic disease

31 March 2020

1 reference

Lens epithelium-derived growth factor: increased survival and decreased DNA breakage of human RPE cells induced by oxidative stress

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2314

1 reference

11 September 2017

1 reference