Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC. (Q39340562)

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2 February 2020

title

Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC (English)

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Mariacristina Valerio

2

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Andrea Sacconi

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author name string

Giovanni Blandino

1

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Mario Cioce

3

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Federica Mori

4

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Luca Casadei

5

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Claudio Pulito

6

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Francesca Biagioni

8

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Giancarlo Cortese

9

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Sergio Galanti

10

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Cesare Manetti

11

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Gennaro Citro

12

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Paola Muti

13

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Sabrina Strano

14

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language of work or name

English

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publication date

29 May 2012

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2 February 2020

published in

Nature Communications

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volume

3

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page(s)

865

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https://scigraph.springernature.com/pub.10.1038/ncomms1859

2 February 2020

exact match

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cites work

Human breast cancer cell lines as models of growth regulation and disease progression

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12 December 2020

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

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12 December 2020

Dicer, Drosha, and outcomes in patients with ovarian cancer

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12 December 2020

Change in lactate production in Myc-transformed cells precedes apoptosis and can be inhibited by Bcl-2 overexpression

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12 December 2020

Regulation of cancer cell metabolism

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12 December 2020

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

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12 December 2020

Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

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12 December 2020

The c-Myc target gene network

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12 December 2020

MicroRNA biogenesis: coordinated cropping and dicing

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12 December 2020

Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors.

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12 December 2020

Metabolic profiles of cancer cells

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12 December 2020

Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells

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12 December 2020

Targeting cancer metabolism: a therapeutic window opens

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12 December 2020

AMP-activated protein kinase and metabolic control

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12 December 2020

Metformin prevents an adaptive increase in GSH and induces apoptosis under the conditions of GSH deficiency in H4IIE cells

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12 December 2020

Metabolic footprinting and systems biology: the medium is the message

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12 December 2020

Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions.

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12 December 2020

Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

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12 December 2020

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

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12 December 2020

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

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12 December 2020

[Effectiveness of metformin in prevention of development of hyperglycemia and neuronal damage caused by ischemic stress]

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12 December 2020

Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class models

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12 December 2020

Metformin increases insulin-stimulated glucose transport in insulin-resistant human skeletal muscle

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12 December 2020

Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types

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12 December 2020

HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferation

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12 December 2020

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

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12 December 2020

Alterations of choline phospholipid metabolism in ovarian tumor progression

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12 December 2020

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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12 December 2020

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

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12 December 2020

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12 December 2020

Cancer cell metabolism: Warburg and beyond

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12 December 2020

Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

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12 December 2020

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

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12 December 2020

The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism

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12 December 2020

Metformin, diet and breast cancer: an avenue for chemoprevention.

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12 December 2020

Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics

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12 December 2020

Characterization of morphological and cytoskeletal changes in MCF10A breast epithelial cells plated on laminin-5: comparison with breast cancer cell line MCF7.

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12 December 2020

MYC-induced cancer cell energy metabolism and therapeutic opportunities

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12 December 2020

Searches for exploitable biochemical differences between normal and cancer cells. VIII. Catabolism of purines and purine nucleotides by sonicates

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12 December 2020

PGC1α confers specificity-metabolic stress and p53-dependent transcription

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12 December 2020

A MicroRNA targeting dicer for metastasis control

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12 December 2020

Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis

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12 December 2020

Role for a bidentate ribonuclease in the initiation step of RNA interference

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12 December 2020

Roles of p53, MYC and HIF-1 in regulating glycolysis - the seventh hallmark of cancer

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12 December 2020

Optimized metabolite extraction from blood serum for 1H nuclear magnetic resonance spectroscopy

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS1859

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2 February 2020

0 references

1 reference

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