Hypothesis: a role for fragile X mental retardation protein in mediating and relieving microRNA-guided translational repression? (Q39344451)

11 September 2017

Hypothesis: a role for fragile X mental retardation protein in mediating and relieving microRNA-guided translational repression? (English)

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11 September 2017

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2

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11 September 2017

Isabelle Plante

1

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11 September 2017

1 January 2006

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Journal of Biomedicine and Biotechnology

11 September 2017

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11 September 2017

2006

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11 September 2017

16806

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11 September 2017

4

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Creative Commons Attribution 3.0 Unported

11 September 2017

start time

1 January 2006

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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MicroRNAs in gene regulation: when the smallest governs it all

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Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs

11 September 2017

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Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes

11 September 2017

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Dual role of TRBP in HIV replication and RNA interference: viral diversion of a cellular pathway or evasion from antiviral immunity?

11 September 2017

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

11 September 2017

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

11 September 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

11 September 2017

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MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies

11 September 2017

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

11 September 2017

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Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

11 September 2017

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Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes

11 September 2017

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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

11 September 2017

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Processing bodies require RNA for assembly and contain nontranslating mRNAs

11 September 2017

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

11 September 2017

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

11 September 2017

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The Drosha-DGCR8 complex in primary microRNA processing

11 September 2017

1 reference

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Processing of primary microRNAs by the Microprocessor complex

11 September 2017

1 reference

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The Microprocessor complex mediates the genesis of microRNAs

11 September 2017

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11 September 2017

Human MicroRNA targets

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Single processing center models for human Dicer and bacterial RNase III

11 September 2017

1 reference

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The fragile X mental retardation protein has nucleic acid chaperone properties

11 September 2017

1 reference

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RISC assembly defects in the Drosophila RNAi mutant armitage.

11 September 2017

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The fragile X mental retardation protein, FMRP, recognizes G-quartets

11 September 2017

1 reference

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Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

The nuclear RNase III Drosha initiates microRNA processing

11 September 2017

1 reference

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Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region

11 September 2017

1 reference

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Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties

11 September 2017

1 reference

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Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

11 September 2017

1 reference

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Ribonuclease activity and RNA binding of recombinant human Dicer

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins

11 September 2017

1 reference

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11 September 2017

1 reference

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

11 September 2017

1 reference

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The ubiquitous nature of RNA chaperone proteins

11 September 2017

1 reference

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A microRNA in a multiple-turnover RNAi enzyme complex

11 September 2017

1 reference

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Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

A decade of molecular studies of fragile X syndrome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

The Fragile X mental retardation protein

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

The fragile X mental retardation protein inhibits translation via interacting with mRNA

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Role for a bidentate ribonuclease in the initiation step of RNA interference

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Evidence that fragile X mental retardation protein is a negative regulator of translation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Biology of the fragile X mental retardation protein, an RNA-binding protein

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Essential role for KH domains in RNA binding: impaired RNA binding by a mutation in the KH domain of FMR1 that causes fragile X syndrome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

RNA chaperones and the RNA folding problem

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

The fragile X mental retardation protein is associated with ribosomes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1559909

Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function

17 June 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F16806

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F16806

Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F16806

Phosphorylation influences the translation state of FMRP-associated polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2FJBB%2F2006%2F16806

21 January 2018

Identifiers

DOI

10.1155/JBB/2006/16806

1 reference

11 September 2017

1 reference

11 September 2017

1 reference

PMCID

1559909