Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases (Q39388766)

11 September 2017

Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases (English)

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11 September 2017

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Timothy P Wakeman

1

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11 September 2017

Qinhong Wang

series ordinal

2

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11 September 2017

Junjie Feng

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3

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11 September 2017

Xiao-Fan Wang

series ordinal

4

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11 September 2017

language of work or name

English

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publication date

28 February 2012

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31

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9

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2169-2181

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describes a project that uses

11 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3343460/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

11 September 2017

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DOT1L regulates dystrophin expression and is critical for cardiac function

11 September 2017

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11 September 2017

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Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B.

11 September 2017

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Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation

11 September 2017

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Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma

11 September 2017

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The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

11 September 2017

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BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression

11 September 2017

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Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis

11 September 2017

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BAT3 interacts with transforming growth factor-beta (TGF-beta) receptors and enhances TGF-beta1-induced type I collagen expression in mesangial cells

11 September 2017

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Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation

11 September 2017

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DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells

11 September 2017

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Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis

11 September 2017

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HLA-B-associated transcript 3 (Bat3)/Scythe is essential for p300-mediated acetylation of p53

11 September 2017

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Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

11 September 2017

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Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L

11 September 2017

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Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9.

11 September 2017

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Complicated tails: histone modifications and the DNA damage response

11 September 2017

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hDOT1L links histone methylation to leukemogenesis

11 September 2017

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The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.

11 September 2017

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Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

11 September 2017

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Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

11 September 2017

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Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase

11 September 2017

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

11 September 2017

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The Paf1 complex is required for histone H3 methylation by COMPASS and Dot1p: linking transcriptional elongation to histone methylation

11 September 2017

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Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

11 September 2017

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Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

11 September 2017

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Dot1p modulates silencing in yeast by methylation of the nucleosome core

11 September 2017

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Histone ubiquitination: a tagging tail unfolds?

11 September 2017

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A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

11 September 2017

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Scythe: a novel reaper-binding apoptotic regulator.

11 September 2017

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Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition.

11 September 2017

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A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain

11 September 2017

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Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation

11 September 2017

1 reference

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Cooperative control of Crb2 by ATM family and Cdc2 kinases is essential for the DNA damage checkpoint in fission yeast

14 September 2017

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Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

25 September 2017

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Free and chromatin-associated mono-, di-, and trimethylation of histone H4-lysine 20 during development and cell cycle progression

17 June 2018

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Solution structure of UIM and interaction of tandem ubiquitin binding domains in STAM1 with ubiquitin

17 June 2018

1 reference

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ES cell cycle progression and differentiation require the action of the histone methyltransferase Dot1L.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

Putting the pieces together: histone H2B ubiquitylation directly stimulates histone H3K79 methylation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

Unique proteasome subunit Xrpn10c is a specific receptor for the antiapoptotic ubiquitin-like protein Scythe

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3343460

21 August 2018

Identifiers

DOI

10.1038/EMBOJ.2012.50

1 reference

11 September 2017

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11 September 2017

PubMed publication ID

22373577

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