Double-stranded Let-7 mimics, potential candidates for cancer gene therapy (Q39446602)

12 September 2017

Double-stranded Let-7 mimics, potential candidates for cancer gene therapy (English)

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12 September 2017

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Qi-zhao Wang

1

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12 September 2017

Ying-hui Lv

2

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12 September 2017

Yu-hua Gong

3

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12 September 2017

Zhao-fa Li

4

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12 September 2017

William Xu

5

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12 September 2017

Yong Diao

6

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12 September 2017

Ruian Xu

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12 September 2017

9 November 2011

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Journal of Physiology and Biochemistry

12 September 2017

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12 September 2017

68

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12 September 2017

1

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12 September 2017

107-119

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https://scigraph.springernature.com/pub.10.1007/s13105-011-0124-0

12 September 2017

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The let-7 microRNA reduces tumor growth in mouse models of lung cancer

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Post-transcriptional gene silencing by siRNAs and miRNAs

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MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

21 January 2018

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

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Integration preferences of wildtype AAV-2 for consensus rep-binding sites at numerous loci in the human genome

21 January 2018

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let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis

21 January 2018

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MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression

21 January 2018

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The let-7 microRNA represses cell proliferation pathways in human cells

21 January 2018

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RAS is regulated by the let-7 microRNA family

21 January 2018

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

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RNAi-based treatment for neovascular age-related macular degeneration by Sirna-027.

21 January 2018

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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Competition for RISC binding predicts in vitro potency of siRNA.

21 January 2018

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Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model

21 January 2018

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Suppression of non-small cell lung tumor development by the let-7 microRNA family

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New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sites

21 January 2018

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The tumor suppressor microRNA let-7 represses the HMGA2 oncogene

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MicroRNA-143 as a tumor suppressor for bladder cancer.

21 January 2018

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Differential expression of components of the microRNA machinery during mouse organogenesis.

21 January 2018

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Principles of cancer therapy: oncogene and non-oncogene addiction

21 January 2018

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A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

21 January 2018

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

21 January 2018

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Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92

21 January 2018

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MicroRNAs in clinical oncology: at the crossroads between promises and problems

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Efficiency of RNA interference in the mouse hematopoietic system varies between cell types and developmental stages

21 January 2018

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An integrated genomic analysis of human glioblastoma multiforme

21 January 2018

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Antiproliferative effects by Let-7 repression of high-mobility group A2 in uterine leiomyoma

21 January 2018

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MicroRNA silencing in primates: towards development of novel therapeutics

21 January 2018

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MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells.

21 January 2018

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Identification of eight members of the Argonaute family in the human genome

21 January 2018

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Asymmetry in the assembly of the RNAi enzyme complex

21 January 2018

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Widespread changes in protein synthesis induced by microRNAs

21 January 2018

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Oncogene addiction: setting the stage for molecularly targeted cancer therapy

21 January 2018

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Let-7 expression defines two differentiation stages of cancer

21 January 2018

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Non-oncogene addiction and the stress phenotype of cancer cells

21 January 2018

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Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

21 January 2018

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Endogenous human microRNAs that suppress breast cancer metastasis

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let-7 MicroRNA transfer in pancreatic cancer-derived cells inhibits in vitro cell proliferation but fails to alter tumor progression

21 January 2018

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Toward microRNA-based therapeutics for heart disease: the sense in antisense

21 January 2018

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Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

21 January 2018

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The design of vectors for RNAi delivery system

21 January 2018

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Potential uses of microRNA in lung cancer diagnosis, prognosis, and therapy

21 January 2018

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21 January 2018

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21 January 2018

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Unique microRNA molecular profiles in lung cancer diagnosis and prognosis

21 January 2018

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let-7 regulates self renewal and tumorigenicity of breast cancer cells

21 January 2018

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MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms

21 January 2018

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The therapeutic potential of microRNA modulation.

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22065350

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Synthetic microRNA and double-stranded RNA targeting the 3'-untranslated region of HER-2/neu mRNA inhibit HER-2 protein expression in ovarian cancer cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065350

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Let-7 microRNA inhibits the proliferation of human glioblastoma cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22065350

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13105-011-0124-0

1 reference

12 September 2017

1 reference