SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis. (Q39488863)

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11 February 2020

title

SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis (English)

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11 February 2020

main subject

neoplastic invasiveness

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3

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11 February 2020

author name string

María R Girotti

1

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11 February 2020

Marisol Fernández

2

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Emilio Camafeita

4

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11 February 2020

Elmer A Fernández

5

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11 February 2020

Juan P Albar

6

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11 February 2020

Lorena G Benedetti

7

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11 February 2020

María P Valacco

8

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11 February 2020

Rolf A Brekken

9

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11 February 2020

Osvaldo L Podhajcer

10

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11 February 2020

Andrea S Llera

11

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11 February 2020

language of work or name

English

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publication date

18 August 2011

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Journal of Investigative Dermatology

11 February 2020

published in

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volume

131

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issue

12

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page(s)

2438-2447

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https://scigraph.springernature.com/pub.10.1038/jid.2011.239

11 February 2020

exact match

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cites work

A High-Throughput Study in Melanoma Identifies Epithelial-Mesenchymal Transition as a Major Determinant of Metastasis

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7 January 2021

Secreted protein acidic and rich in cysteine produced by human melanoma cells modulates polymorphonuclear leukocyte recruitment and antitumor cytotoxic capacity.

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7 January 2021

Growth control by intracellular tension and extracellular stiffness

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Induction of TGF-beta1 by the matricellular protein SPARC in a rat model of glomerulonephritis

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7 January 2021

SPARC, a matricellular protein that functions in cellular differentiation and tissue response to injury

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7 January 2021

SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength

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7 January 2021

SPARC, a matricellular protein: at the crossroads of cell-matrix communication

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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

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Dynamic interplay between the collagen scaffold and tumor evolution

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7 January 2021

The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

SPARC regulates the expression of collagen type I and transforming growth factor-beta1 in mesangial cells.

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7 January 2021

Mapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens

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7 January 2021

Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles

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7 January 2021

Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro.

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Increased SPARC expression promotes U87 glioblastoma invasion in vitro

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystatin C and is relieved by neutrophil elastase

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Contact of high-invasive, but not low-invasive, melanoma cells to native collagen I induces the release of mature cathepsin B.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Interaction of human breast fibroblasts with collagen I increases secretion of procathepsin B.

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7 January 2021

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

The expression of the secreted protein acidic and rich in cysteine (SPARC) is associated with the neoplastic progression of human melanoma.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Suppression of SPARC expression by antisense RNA abrogates the tumorigenicity of human melanoma cells

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7 January 2021

The amyloid-beta peptide suppresses transforming growth factor-beta1-induced matrix metalloproteinase-2 production via Smad7 expression in human monocytic THP-1 cells.

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7 January 2021

Matrix crosslinking forces tumor progression by enhancing integrin signaling

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7 January 2021

Dynamics of intercellular communication during melanoma development

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7 January 2021

Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Exocytosis of active cathepsin B enzyme activity at pH 7.0, inhibition and molecular mass

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

https://api.crossref.org/works/10.1038%2FJID.2011.239

1 reference

7 January 2021

Osteonectin expression correlates with clinical outcome in thin cutaneous malignant melanomas

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Cysteine cathepsins: multifunctional enzymes in cancer

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7 January 2021

The morphological and molecular features of the epithelial-to-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

TGF-beta 1 induces the expression of type I collagen and SPARC, and enhances contraction of collagen gels, by fibroblasts from young and aged donors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Increased carcinogenic potential of myeloid tumor cells induced by aberrant TGF-beta1-signaling and upregulation of cathepsin B.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

SPARC represses E-cadherin and induces mesenchymal transition during melanoma development

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Pericellular cathepsin B and malignant progression

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Limited cleavage of extracellular matrix protein BM-40 by matrix metalloproteinases increases its affinity for collagens

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

SPARC Inhibits Epithelial Cell Proliferation in Part through Stimulation of the Transforming Growth Factor-β–Signaling System

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Collagen I-mediated up-regulation of N-cadherin requires cooperative signals from integrins and discoidin domain receptor 1

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Osteonectin downregulates E-cadherin, induces osteopontin and focal adhesion kinase activity stimulating an invasive melanoma phenotype.

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Proteomic analysis identified N-cadherin, clusterin, and HSP27 as mediators of SPARC (secreted protein, acidic and rich in cysteines) activity in melanoma cells

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Epithelial-mesenchymal transitions in development and disease

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https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

PANTHER: a library of protein families and subfamilies indexed by function

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7 January 2021

PANTHER: a browsable database of gene products organized by biological function, using curated protein family and subfamily classification

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Management of cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Crystal structure of cathepsin B inhibited with CA030 at 2.0-A resolution: A basis for the design of specific epoxysuccinyl inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Identifying the SPARC binding sites on collagen I and procollagen I by atomic force microscopy

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

The copper binding domain of SPARC mediates cell survival in vitro via interaction with integrin beta1 and activation of integrin-linked kinase

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Mechanisms of the epithelial-mesenchymal transition by TGF-beta

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Attenuation of collagen production with small interfering RNA of SPARC in cultured fibroblasts from the skin of patients with scleroderma.

1 reference

https://api.crossref.org/works/10.1038%2FJID.2011.239

7 January 2021

Identifiers

DOI

10.1038/JID.2011.239

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21850018%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference