Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells (Q39490308)

12 September 2017

Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells (English)

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12 September 2017

P T Ferrao

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12 September 2017

E P Bukczynska

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12 September 2017

R W Johnstone

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12 September 2017

G A McArthur

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12 September 2017

language of work or name

English

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publication date

15 August 2011

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12 September 2017

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12 September 2017

31

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12 September 2017

1661-1672

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12 September 2017

13

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https://scigraph.springernature.com/pub.10.1038/onc.2011.358

12 September 2017

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New insights into checkpoint kinase 1 in the DNA damage response signaling network

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Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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Probing the human kinome for kinases involved in pancreatic cancer cell survival and gemcitabine resistance

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ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress

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Genomic instability--an evolving hallmark of cancer

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Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin

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Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

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Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control

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Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.

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AZD7762, a novel checkpoint kinase inhibitor, drives checkpoint abrogation and potentiates DNA-targeted therapies

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Status of p53 in human cancer cells does not predict efficacy of CHK1 kinase inhibitors combined with chemotherapeutic agents

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Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

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c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2011.358

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Dimensions Publication ID

12 September 2017

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