Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study (Q39552115)

13 September 2017

Serum gamma-glutamyl transferase and risk of type 2 diabetes in the general Korean population: a Mendelian randomization study (English)

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13 September 2017

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13 September 2017

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13 September 2017

Caroline L Relton

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author name string

Youn Sue Lee

1

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13 September 2017

Yoonsu Cho

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13 September 2017

So-Youn Shin

6

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13 September 2017

Min-Jeong Shin

7

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13 September 2017

27 July 2016

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13 September 2017

Human Molecular Genetics

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13 September 2017

25

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13 September 2017

3877-3886

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13 September 2017

17

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A genome-wide association study identifies novel risk loci for type 2 diabetes

13 September 2017

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Liver enzymes and incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study

21 January 2018

1 reference

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The association of central obesity with type 2 diabetes among Koreans according to the serum gamma-glutamyltransferase level: Korean genome and epidemiology study

21 January 2018

1 reference

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Association of serum gamma-glutamyltransferase and alanine aminotransferase activities with risk of type 2 diabetes mellitus independent of fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Liver enzymes, race, gender and diabetes risk: the Atherosclerosis Risk in Communities (ARIC) Study

21 January 2018

1 reference

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The association between liver enzymes and risk of type 2 diabetes: the Namwon study

21 January 2018

1 reference

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Elevated serum GGT concentrations predict reduced insulin sensitivity and increased intrahepatic lipids

21 January 2018

1 reference

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Clinical association between serum γ-glutamyltransferase levels and the development of insulin resistance in Korean men: a 5-year follow-up study

21 January 2018

1 reference

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Assessment of the fatty liver index as an indicator of hepatic steatosis for predicting incident diabetes independently of insulin resistance in a Korean population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

21 January 2018

1 reference

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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

21 January 2018

1 reference

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Methodological challenges in mendelian randomization

21 January 2018

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Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

21 January 2018

1 reference

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Biological, clinical and population relevance of 95 loci for blood lipids

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Common variants at 30 loci contribute to polygenic dyslipidemia

21 January 2018

1 reference

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

21 January 2018

1 reference

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New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population

21 January 2018

1 reference

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New loci associated with kidney function and chronic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Discovery and refinement of loci associated with lipid levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

New variants including ARG1 polymorphisms associated with C-reactive protein levels identified by genome-wide association and pathway analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Serum gamma-glutamyl transferase within its normal concentration range is related to the presence of impaired fasting glucose and diabetes among Japanese community-dwelling persons

21 January 2018

1 reference

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Serum gamma-glutamyl transferase level and diabetes mellitus among US adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Adipocytokines, hepatic and inflammatory biomarkers and incidence of type 2 diabetes. the CoLaus study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Gamma-glutamyl transferase and risk of type II diabetes: an updated systematic review and dose-response meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Gamma-glutamyl transpeptidase and the metabolic syndrome.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Aminotransferase and gamma-glutamyltranspeptidase levels in obesity are associated with insulin resistance and the metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Use of a Mendelian randomization approach to assess the causal relation of gamma-Glutamyltransferase with blood pressure and serum insulin levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Structural, Functional, and Clinical Aspects of γ-Glutamyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

High-level expression of enzymatically active mature human gamma-glutamyltransferase in transgenic V79 Chinese hamster cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Avoiding bias from weak instruments in Mendelian randomization studies

21 January 2018

1 reference

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The significance of serum gamma-glutamyltransferase in cardiovascular diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Variation in the γ-glutamyltransferase 1 gene and risk of chronic pancreatitis

21 January 2018

1 reference

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Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis

21 January 2018

1 reference

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Tumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1.

21 January 2018

1 reference

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Mendelian randomization in health research: using appropriate genetic variants and avoiding biased estimates

21 January 2018

1 reference

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Identifying the odds ratio estimated by a two-stage instrumental variable analysis with a logistic regression model

21 January 2018

1 reference

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Use of Mendelian randomisation to assess potential benefit of clinical intervention

21 January 2018

1 reference

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A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.

21 January 2018

1 reference

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A new multipoint method for genome-wide association studies by imputation of genotypes

21 January 2018

1 reference

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Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDW226

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

21 January 2018

1 reference

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Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

21 January 2018

1 reference

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Two-Sample Instrumental Variables Estimators

21 January 2018

1 reference

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Abnormal Liver Function Test Predicts Type 2 Diabetes: A community-based prospective study

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/HMG/DDW226

1 reference

13 September 2017

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