Genetic and functional heterogeneity of CNS-derived tat alleles from patients with HIV-associated dementia (Q39619066)

13 September 2017

title

Genetic and functional heterogeneity of CNS-derived tat alleles from patients with HIV-associated dementia (English)

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13 September 2017

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13 September 2017

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Steven L Wesselingh

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13 September 2017

Daniel Cowley

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13 September 2017

Paul R Gorry

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4

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13 September 2017

Melissa J Churchill

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5

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13 September 2017

publication date

30 November 2010

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13 September 2017

published in

Journal of NeuroVirology

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13 September 2017

volume

17

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13 September 2017

issue

1

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13 September 2017

page(s)

70-81

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CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable

13 September 2017

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Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

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TAR-independent activation of HIV-1 requires the activation domain but not the RNA-binding domain of Tat.

21 January 2018

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12 December 2020

Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry

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12 December 2020

Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues

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12 December 2020

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12 December 2020

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12 December 2020

Persistent human immunodeficiency virus type 1 infection in human fetal glial cells reactivated by T-cell factor(s) or by the cytokines tumor necrosis factor alpha and interleukin-1 beta

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12 December 2020

Brain-derived HIV-1 tat sequences from AIDS patients with dementia show increased molecular heterogeneity.

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12 December 2020

Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

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12 December 2020

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

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12 December 2020

Functional domains required for tat-induced transcriptional activation of the HIV-1 long terminal repeat

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12 December 2020

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

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12 December 2020

An infectious molecular clone of an unusual macrophage-tropic and highly cytopathic strain of human immunodeficiency virus type 1

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12 December 2020

Viral phenotype and fitness.

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12 December 2020

Molecular dynamics simulations on HIV-1 Tat

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12 December 2020

Structural analysis of wild-type and mutant human immunodeficiency virus type 1 Tat proteins

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12 December 2020

Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy

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12 December 2020

Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes

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12 December 2020

Mutational analysis of the conserved cysteine-rich region of the human immunodeficiency virus type 1 Tat protein

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12 December 2020

Mechanisms of transcriptional transactivation and restriction of human immunodeficiency virus type I replication in an astrocytic glial cell.

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12 December 2020

Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic

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12 December 2020

Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis

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12 December 2020

Inhibition of human immunodeficiency virus type 1 and type 2 Tat function by transdominant Tat protein localized to both the nucleus and cytoplasm

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12 December 2020

A second-site mutation that restores replication of a Tat-defective human immunodeficiency virus

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12 December 2020

Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

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12 December 2020

10.1007/S13365-010-0002-5

Identifiers

DOI

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13 September 2017

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