V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling. (Q39631621)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078678%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

V3 versican isoform alters the behavior of human melanoma cells by interfering with CD44/ErbB-dependent signaling (English)

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16 January 2020

2

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16 January 2020

María Jose Docampo

3

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16 January 2020

Anna Bassols

7

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16 January 2020

author name string

Daniel Hernández

1

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16 January 2020

Anna Marco-Ramell

4

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16 January 2020

Jennifer Cabrera

5

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16 January 2020

Angels Fabra

6

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16 January 2020

language of work or name

English

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publication date

15 November 2010

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Journal of Biological Chemistry

16 January 2020

published in

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16 January 2020

volume

286

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16 January 2020

issue

2

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16 January 2020

page(s)

1475-1485

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The biological role and regulation of versican levels in cancer.

16 January 2020

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Hyaluronan, CD44, and cyclooxygenase-2 in colon cancer

14 September 2017

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Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells

14 September 2017

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CD44-dependent intracellular and extracellular catabolism of hyaluronic acid by hyaluronidase-1 and -2

14 September 2017

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High stromal versican expression predicts unfavourable outcome in oral squamous cell carcinoma

14 September 2017

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Transforming growth factor-beta as a key molecule triggering the expression of versican isoforms v0 and v1, hyaluronan synthase-2 and synthesis of hyaluronan in malignant osteosarcoma cells

14 September 2017

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Chemotaxis towards hyaluronan is dependent on CD44 expression and modulated by cell type variation in CD44-hyaluronan binding.

14 September 2017

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The interaction of versican with its binding partners

14 September 2017

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CD44 in cancer progression: adhesion, migration and growth regulation

14 September 2017

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Distinct interaction of versican/PG-M with hyaluronan and link protein

14 September 2017

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Versican: a versatile extracellular matrix proteoglycan in cell biology

14 September 2017

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CD44-mediated uptake and degradation of hyaluronan

14 September 2017

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Ras participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1

14 September 2017

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Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth

14 September 2017

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Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways.

14 September 2017

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Matrix proteoglycans: from molecular design to cellular function

14 September 2017

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A novel glycosaminoglycan attachment domain identified in two alternative splice variants of human versican

14 September 2017

1 reference

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Inhibition of CD44 expression by small interfering RNA to suppress the growth and metastasis of ovarian cancer cells in vitro and in vivo

14 September 2017

1 reference

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Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

14 September 2017

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

14 September 2017

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Suppression of human colon cancer tumors in nude mice by siRNA CD44 gene therapy

14 September 2017

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Inhibition of malignant activities of nasopharyngeal carcinoma cells with high expression of CD44 by siRNA.

14 September 2017

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Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration

14 September 2017

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V3 versican isoform expression has a dual role in human melanoma tumor growth and metastasis.

14 September 2017

1 reference

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Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer

14 September 2017

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ErbB receptors mediate both migratory and proliferative activities in human melanocytes and melanoma cells.

14 September 2017

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Hyaluronan constitutively regulates ErbB2 phosphorylation and signaling complex formation in carcinoma cells.

14 September 2017

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CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion

14 September 2017

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The heregulin/human epidermal growth factor receptor as a new growth factor system in melanoma with multiple ways of deregulation

14 September 2017

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Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

14 September 2017

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The G3 domain of versican enhances cell proliferation via epidermial growth factor-like motifs

25 September 2017

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17 June 2018

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Versican in nonsmall cell lung cancer: relation to hyaluronan, clinicopathologic factors, and prognosis

17 June 2018

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V3 versican isoform expression alters the phenotype of melanoma cells and their tumorigenic potential.

21 August 2018

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Expression of extracellular matrix components versican, chondroitin sulfate, tenascin, and hyaluronan, and their association with disease outcome in node-negative breast cancer

21 August 2018

1 reference

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Versican in epithelial ovarian cancer: Relation to hyaluronan, clinicopathologic factors and prognosis

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020756

Expression of the proteoglycans versican and mel-CSPG in dysplastic nevi.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020756

Versican is differentially expressed in human melanoma and may play a role in tumor development.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020756

Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.

21 August 2018

1 reference

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SB203580 promotes EGF-stimulated early morphological differentiation in PC12 cell through activating ERK pathway

21 August 2018

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Multiple forms of mouse PG-M, a large chondroitin sulfate proteoglycan generated by alternative splicing

21 August 2018

1 reference

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Regulation of stromal versican expression by breast cancer cells and importance to relapse-free survival in patients with node-negative primary breast cancer

21 August 2018

1 reference

12 December 2020

Internalization of hyaluronan by chondrocytes occurs via receptor-mediated endocytosis

1 reference

12 December 2020

2B1 antigen characteristically expressed on extracellular matrices of human malignant tumors is a large chondroitin sulfate proteoglycan, PG-M/versican

1 reference

12 December 2020

Elevated levels of versican but not decorin predict disease progression in early-stage prostate cancer

1 reference

12 December 2020

Divergent roles for Ras and Rap in the activation of p38 mitogen-activated protein kinase by interleukin-1

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12 December 2020

Promotion of chondrocyte proliferation by versican mediated by G1 domain and EGF-like motifs

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.127522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078678%20AND%20SRC:MED&resulttype=core&format=json

release_mux4ayutdjaw3c4apzn3d6iuui

16 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mux4ayutdjaw3c4apzn3d6iuui

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21078678%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

21078678

1 reference