Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes. (Q39633310)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Amy R Cameron

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Siji Anil

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Emma Sutherland

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Jean Harthill

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

1 reference

19 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

195-203

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21069157%20AND%20SRC:MED&resulttype=core&format=json

The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation

16 January 2020

cites work

1 reference

Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX.

21 January 2018

1 reference

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

21 January 2018

1 reference

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

1 reference

Negative regulation of the forkhead transcription factor FKHR by Akt.

21 January 2018

1 reference

Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway

21 January 2018

1 reference

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

21 January 2018

1 reference

Correlation between FOXO1a (FKHR) and FOXO3a (FKHRL1) binding and the inhibition of basal glucose-6-phosphatase catalytic subunit gene transcription by insulin

21 January 2018

1 reference

The three insulin response sequences in the glucose-6-phosphatase catalytic subunit gene promoter are functionally distinct

21 January 2018

1 reference

Antagonistic effects of phorbol esters on insulin regulation of insulin-like growth factor-binding protein-1 (IGFBP-1) but not glucose-6-phosphatase gene expression

21 January 2018

1 reference

Different mechanisms are used by insulin to repress three genes that contain a homologous thymine-rich insulin response element

21 January 2018

1 reference

Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure

21 January 2018

1 reference

Characterization of a protein kinase B inhibitor in vitro and in insulin-treated liver cells

21 January 2018

1 reference

Targeting foxo1 in mice using antisense oligonucleotide improves hepatic and peripheral insulin action.

21 January 2018

1 reference

FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

21 January 2018

1 reference

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

21 January 2018

1 reference

Cellular mechanisms of insulin resistance

21 January 2018

1 reference

Black tea polyphenols mimic insulin/insulin-like growth factor-1 signalling to the longevity factor FOXO1a

21 January 2018

1 reference

Differences in the nature of the interaction of insulin and proinsulin with zinc

21 January 2018

1 reference

Is the evolution of insulin Darwinian or due to selectively neutral mutation?

21 January 2018

1 reference

Role of zinc in insulin biosynthesis. Some possible zinc-insulin interactions in the pancreatic B-cell

21 January 2018

1 reference

Structural stability in the 4-zinc human insulin hexamer

21 January 2018

1 reference

Comparison of solution structural flexibility and zinc binding domains for insulin, proinsulin, and miniproinsulin

21 January 2018

1 reference

Effects of zinc ion on the conformation of antigenic determinants on insulin

21 January 2018

1 reference

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

21 January 2018

1 reference

Intracellular zinc fluctuations modulate protein tyrosine phosphatase activity in insulin/insulin-like growth factor-1 signaling.

21 January 2018

1 reference

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions

21 January 2018

1 reference

Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences.

21 January 2018

1 reference

Insulinomimetic Zn complex (Zn(opt)2) enhances insulin signaling pathway in 3T3-L1 adipocytes

21 January 2018

1 reference

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

21 January 2018

1 reference

Epigallocatechin gallate (EGCG) mimics insulin action on the transcription factor FOXO1a and elicits cellular responses in the presence and absence of insulin

21 January 2018

1 reference

D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

21 January 2018

1 reference

Is zinc a neuromodulator?

21 January 2018

1 reference

Coordination of aluminium with purpurogallin and theaflavin digallate

21 January 2018

1 reference

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species

21 January 2018

1 reference

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

Molecular targets of lithium action

21 January 2018

1 reference

Use of Akt inhibitor and a drug-resistant mutant validates a critical role for protein kinase B/Akt in the insulin-dependent regulation of glucose and system A amino acid uptake

21 January 2018

1 reference

Protein tyrosine phosphatases as targets of the combined insulinomimetic effects of zinc and oxidants

21 January 2018

1 reference

A Polymorphism in the Zinc Transporter Gene SLC30A8 Confers Resistance Against Posttransplantation Diabetes Mellitus in Renal Allograft Recipients

21 January 2018

1 reference