Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix. (Q39638881)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21028803%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Highly efficient gene silencing activity of siRNA embedded in a nanostructured gyroid cubic lipid matrix (English)

1 reference

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15 January 2020

0 references

3

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15 January 2020

Cyrus R Safinya

series ordinal

4

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15 January 2020

author name string

Cecília Leal

series ordinal

1

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15 January 2020

Nathan F Bouxsein

series ordinal

2

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15 January 2020

language of work or name

English

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publication date

28 October 2010

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Journal of the American Chemical Society

15 January 2020

published in

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15 January 2020

volume

132

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15 January 2020

issue

47

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15 January 2020

page(s)

16841-16847

1 reference

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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

15 January 2020

cites work

1 reference

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Gene therapy clinical trials worldwide to 2007--an update.

14 September 2017

1 reference

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An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents

14 September 2017

1 reference

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RNA interference and potential therapeutic applications of short interfering RNAs

14 September 2017

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Cationic lipid-DNA complexes for non-viral gene therapy: relating supramolecular structures to cellular pathways

14 September 2017

1 reference

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Unlocking the potential of the human genome with RNA interference

14 September 2017

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Gene therapy clinical trials worldwide 1989-2004-an overview.

14 September 2017

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14 September 2017

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RNAi as a gene therapy approach

14 September 2017

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Progress and problems with the use of viral vectors for gene therapy

14 September 2017

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Three-Dimensional Imaging of Lipid Gene-Carriers: Membrane Charge Density Controls Universal Transfection Behavior in Lamellar Cationic Liposome-DNA Complexes

14 September 2017

1 reference

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Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

14 September 2017

1 reference

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Gene silencing in mammals by small interfering RNAs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Observation of a membrane fusion intermediate structure

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Analysis of gene function in somatic mammalian cells using small interfering RNAs

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Post-transcriptional gene silencing by double-stranded RNA

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Post-transcriptional gene silencing across kingdoms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Evidence for the role of proteoglycans in cation-mediated gene transfer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

The mechanism of lamellar-to-inverted hexagonal phase transitions in phosphatidylethanolamine: implications for membrane fusion mechanisms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

An electron microscopy study into the mechanism of gene transfer with lipopolyamines.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2991473

Elastic properties of lipid bilayers: theory and possible experiments

15 June 2018

1 reference

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Medicine. Gene therapy--new challenges ahead

15 June 2018

1 reference

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Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes

21 August 2018

1 reference

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Chalcone synthase cosuppression phenotypes in petunia flowers: comparison of sense vs. antisense constructs and single-copy vs. complex T-DNA sequences

21 August 2018

1 reference

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Cellular and molecular barriers to gene transfer by a cationic lipid

21 August 2018

1 reference

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21 August 2018

Identifiers

DOI

10.1021/JA1059763

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21028803%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21028803%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference