Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response (Q24294875)

GOA release 2020-03-11

tumor protein p53

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negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

GOA release 2020-03-11

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WAF1, a potential mediator of p53 tumor suppression

GOA release 2020-03-11

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3

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author name string

Xiaolong Wei

series ordinal

1

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Hai Xu

series ordinal

2

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language of work or name

English

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publication date

February 2005

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published in

Cancer Cell

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volume

7

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issue

2

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page(s)

167-78

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cites work

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Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

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p53, the cellular gatekeeper for growth and division

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Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells

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A novel cofactor for p300 that regulates the p53 response

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PUMA induces the rapid apoptosis of colorectal cancer cells

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Transcriptional regulation by p53 through intrinsic DNA/chromatin binding and site-directed cofactor recruitment.

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ASPP proteins specifically stimulate the apoptotic function of p53

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7 January 2021

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

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p53 Functions through Stress- and Promoter-Specific Recruitment of Transcription Initiation Components before and after DNA Damage

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Structural mechanism of the bromodomain of the coactivator CBP in p53 transcriptional activation

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7 January 2021

p21Waf1/Cip1 as a therapeutic target in breast and other cancers

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7 January 2021

Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents

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7 January 2021

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

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7 January 2021

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

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7 January 2021

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

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7 January 2021

Segregation of receptor and ligand regulates activation of epithelial growth factor receptor

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7 January 2021

The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

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7 January 2021

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

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7 January 2021

Nuclear transport and cancer: from mechanism to intervention

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7 January 2021

Live or let die: the cell's response to p53

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Decision making by p53: life, death and cancer

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7 January 2021

Human DF3/MUC1 carcinoma-associated protein functions as an oncogene

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7 January 2021

MUC1 overexpression results in mammary gland tumorigenesis and prolonged alveolar differentiation

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7 January 2021

Chromatin immunoprecipitation analysis fails to support the latency model for regulation of p53 DNA binding activity in vivo

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7 January 2021

Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response

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7 January 2021

Isolation and sequencing of a cDNA coding for the human DF3 breast carcinoma-associated antigen

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7 January 2021

Wild-type p53 binds to the TATA-binding protein and represses transcription

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7 January 2021

Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase

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7 January 2021

Transactivation ability of p53 transcriptional activation domain is directly related to the binding affinity to TATA-binding protein

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7 January 2021

Genotoxic drugs induce interaction of the c-Abl tyrosine kinase and the tumor suppressor protein p53.

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7 January 2021

Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Physical and functional interaction between p53 and the Werner's syndrome protein

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Ligand-dependent formation of retinoid receptors, receptor-interacting protein 140 (RIP140), and histone deacetylase complex is mediated by a novel receptor-interacting motif of RIP140

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland

1 reference

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7 January 2021

p73β Is Regulated by Protein Kinase Cδ Catalytic Fragment Generated in the Apoptotic Response to DNA Damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

The activation domains, the proline-rich domain, and the C-terminal basic domain in p53 are necessary for acetylation of histones on the proximal p21 promoter and interaction with p300/CREB-binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Physical and functional interactions between PML and MDM2

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

The cyclin-dependent kinase inhibitor p21CIP/WAF is a positive regulator of insulin-like growth factor I-induced cell proliferation in MCF-7 human breast cancer cells

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7 January 2021

Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...]

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Nuclear association of the cytoplasmic tail of MUC1 and beta-catenin.

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7 January 2021

MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Differential Reactivity of a Novel Monoclonal Antibody (DF3) with Human Malignant versus Benign Breast Tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Excess beta-catenin promotes accumulation of transcriptionally active p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

hADA3 is required for p53 activity

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Identification of redox/repair protein Ref-1 as a potent activator of p53

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

p53-mediated apoptosis is attenuated in Werner syndrome cells

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Kinetics of p53 binding to promoter sites in vivo

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Down-regulation of beta-catenin by activated p53.

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

Novel function of the cyclin A binding site of E2F in regulating p53-induced apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021

DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7

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https://api.crossref.org/works/10.1016%2FJ.CCR.2005.01.008

7 January 2021