AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling (Q39687751)

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scientific article published on 28 June 2010

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English	AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling	scientific article published on 28 June 2010

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scholarly article

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Europe PubMed Central

14 September 2017

AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal-to-epithelial transdifferentiation by inhibiting TGF-β-mediated ERK signaling (English)

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Europe PubMed Central

14 September 2017

pancreatic cancer

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inferred from title

10

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H Friess

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Europe PubMed Central

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author name string

B Kong

1

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Europe PubMed Central

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C W Michalski

2

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Europe PubMed Central

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X Hong

3

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Europe PubMed Central

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N Valkovskaya

4

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Europe PubMed Central

14 September 2017

S Rieder

5

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Europe PubMed Central

14 September 2017

I Abiatari

6

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Europe PubMed Central

14 September 2017

S Streit

7

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Europe PubMed Central

14 September 2017

M Erkan

8

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Europe PubMed Central

14 September 2017

I Esposito

9

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Europe PubMed Central

14 September 2017

J Kleeff

11

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14 September 2017

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publication date

28 June 2010

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Europe PubMed Central

14 September 2017

29

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37

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5146-5158

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https://scigraph.springernature.com/pub.10.1038/onc.2010.258

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Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1.

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TGFbeta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest

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Induction of lipolysis in vitro and loss of body fat in vivo by zinc-alpha2-glycoprotein.

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Immunohistochemical localization of Zn-alpha 2-glycoprotein in normal human tissues

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SCF(beta-TrCP1) controls Smad4 protein stability in pancreatic cancer cells

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Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

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Structural and energetic aspects of Grb2-SH2 domain-swapping

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Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell line

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Zinc-alpha2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia.

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Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression

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Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

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Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

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Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma

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Zn-α2-glycoprotein levels in breast cancer cytosols and correlation with clinical, histological and biochemical parameters

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Sustained induction of epithelial to mesenchymal transition activates DNA methylation of genes silenced in basal-like breast cancers

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Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer

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High hopes for p21 in cancer treatment

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Cyclin degradation for cancer therapy and chemoprevention

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The major 40-kDa glycoprotein in human prostatic fluid is identical to Zn-alpha 2-glycoprotein

1 reference

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HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

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Growth factor-dependent activation of the Ras-Raf-MEK-MAPK pathway in the human pancreatic carcinoma cell line PANC-1 carrying activated K-ras: implications for cell proliferation and cell migration

1 reference

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Histone deacetylases and cancer

1 reference

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Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

1 reference

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Bone morphogenetic protein 4 induces epithelial-mesenchymal transition through MSX2 induction on pancreatic cancer cell line

1 reference

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Role of Ras signaling in the induction of snail by transforming growth factor-beta.

1 reference

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Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

1 reference

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

1 reference

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Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway

1 reference

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Inflammation and mitochondrial fatty acid beta-oxidation link obesity to early tumor promotion

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

1 reference

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Ki-ras oncogene activation in preinvasive pancreatic cancer

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Egr-1 and serum response factor are involved in growth factors- and serum-mediated induction of E2-EPF UCP expression that regulates the VHL-HIF pathway

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What is the true rate of K-ras mutation in carcinoma of the pancreas?

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Grb2 SH2 domain-binding peptide analogs as potential anticancer agents

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ZAG, a lipid mobilizing adipokine, is downregulated in human obesity

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Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

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Cannabinoids ameliorate pain and reduce disease pathology in cerulein-induced acute pancreatitis

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Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells

1 reference

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Neurokinin-2 receptor levels correlate with intensity, frequency, and duration of pain in chronic pancreatitis.

1 reference

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Physical activity, obesity, height, and the risk of pancreatic cancer

1 reference

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Human seminal plasma Zn-alpha 2-glycoprotein: its purification and properties as compared with human plasma Zn-alpha 2-glycoprotein

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The two faces of transforming growth factor beta in carcinogenesis

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Epithelial-to-mesenchymal transition confers resistance to apoptosis in three murine mammary epithelial cell lines

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Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice.

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Antidiabetic properties of zinc-alpha2-glycoprotein in ob/ob mice.

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A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

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Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.

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E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/HDAC2 repressor complex

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Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

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Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells

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Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival

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7 January 2021

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10.1038/ONC.2010.258

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Europe PubMed Central

14 September 2017

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Europe PubMed Central

14 September 2017

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