Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor. (Q39688686)

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scientific article published on 13 June 2016

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English	Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor.	scientific article published on 13 June 2016

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27294372%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor (English)

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13 March 2020

Putative nonribosomal peptide synthetase

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Aspergillus nidulans

1 reference

1 reference

author name string

Hsu-Hua Yeh

1

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13 March 2020

Manmeet Ahuja

2

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13 March 2020

Yi-Ming Chiang

3

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13 March 2020

C Elizabeth Oakley

4

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13 March 2020

Shauna Moore

5

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13 March 2020

Olivia Yoon

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13 March 2020

Heather Hajovsky

7

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13 March 2020

Jin-Woo Bok

8

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13 March 2020

Nancy P Keller

9

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13 March 2020

Clay C C Wang

10

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13 March 2020

Berl R Oakley

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13 March 2020

publication date

21 June 2016

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13 March 2020

full work available at URL

https://europepmc.org/articles/pmc6457343?pdf=render

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19 March 2024

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ACS Chemical Biology

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13 March 2020

11

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13 March 2020

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13 March 2020

2275-2284

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13 March 2020

online access status

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19 March 2024

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access restriction status

1 reference

based on heuristic

inferred from online access status

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

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Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of increased dosage of the ML-236B (compactin) biosynthetic gene cluster on ML-236B production in Penicillium citrinum

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

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The thiobacilli

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A versatile and efficient gene-targeting system for Aspergillus nidulans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fusion PCR and gene targeting in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibition by fellutamide B induces nerve growth factor synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromatin-level regulation of biosynthetic gene clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis for mycophenolic acid biosynthesis in Penicillium brevicompactum

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasome inhibitors: an expanding army attacking a unique target

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of the echinocandin B biosynthetic gene cluster from Emericella rugulosa NRRL 11440.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tools for manipulation of secondary metabolism pathways: rapid promoter replacements and gene deletions in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of proteasome inhibitors as research tools and cancer drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accurate prediction of secondary metabolite gene clusters in filamentous fungi

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An efficient system for heterologous expression of secondary metabolite genes in Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of fellutamide B and deoxy-fellutamides B, C, and D.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prototype of an intertwined secondary-metabolite supercluster

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seven new and two known lipopeptides as well as five known polyketides: the activated production of silent metabolites in a marine-derived fungus by chemical mutagenesis strategy using diethyl sulphate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale metabolomics reveals a complex response of Aspergillus nidulans to epigenetic perturbation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translating biosynthetic gene clusters into fungal armor and weaponry

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitotic gene conversion, reciprocal recombination and gene replacement at the benA, beta-tubulin, locus of Aspergillus nidulans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and preliminary characterization of alcohol dehydrogenase from Aspergillus nidulans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-angiogenic agent fumagillin covalently modifies a conserved active-site histidine in the Escherichia coli methionine aminopeptidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/27294372

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1021/ACSCHEMBIO.6B00213

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13 March 2020

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13 March 2020

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13 March 2020

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