Apoptotic induction by simvastatin in human lung cancer A549 cells via Akt signaling dependent down-regulation of survivin (Q39704441)

14 September 2017

title

Apoptotic induction by simvastatin in human lung cancer A549 cells via Akt signaling dependent down-regulation of survivin (English)

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14 September 2017

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Ki-Eun Hwang

1

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14 September 2017

Kyoung-Suk Na

2

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14 September 2017

Do-Sim Park

3

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14 September 2017

Keum-Ha Choi

4

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14 September 2017

Byoung-Ryun Kim

5

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14 September 2017

Hyeok Shim

6

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14 September 2017

Eun-Taik Jeong

7

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14 September 2017

Hak-Ryul Kim

8

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14 September 2017

publication date

13 May 2010

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Investigational New Drugs

14 September 2017

published in

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14 September 2017

volume

29

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14 September 2017

issue

5

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14 September 2017

page(s)

945-952

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14 September 2017

cites work

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The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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Phosphatidylinositol 3-kinase/Akt regulates angiotensin II-induced inhibition of apoptosis in microvascular endothelial cells by governing survivin expression and suppression of caspase-3 activity

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Fibronectin Protects Prostate Cancer Cells from Tumor Necrosis Factor-α-induced Apoptosis via the AKT/Survivin Pathway

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Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

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A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy

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12 December 2020

High expression of Survivin, mapped to 17q25, is significantly associated with poor prognostic factors and promotes cell survival in human neuroblastoma

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12 December 2020

Downregulation of survivin expression and elevation of caspase-3 activity involved in pitavastatin-induced HepG 2 cell apoptosis

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12 December 2020

Expression of the apoptosis inhibitor protein Survivin in primary laryngeal carcinoma and cervical lymph node metastasis

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12 December 2020

Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer.

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12 December 2020

Regulation of survivin expression by IGF-1/mTOR signaling

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12 December 2020

A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non-small-cell lung cancers.

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12 December 2020

Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis.

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12 December 2020

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12 December 2020

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DNA demethylase is expressed in ovarian cancers and the expression correlates with demethylation of CpG sites in the promoter region of c-erbB-2 and survivin genes

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The statins as anticancer agents

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Elevated expression of inhibitor of apoptosis proteins in prostate cancer

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12 December 2020

10.1007/S10637-010-9450-2

Identifiers

DOI

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14 September 2017

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