Comparison of the anti-allergic activity of Syk inhibitors with optimized Syk siRNAs in FcepsilonRI-activated RBL-2H3 basophilic cells (Q39755395)

14 September 2017

Comparison of the anti-allergic activity of Syk inhibitors with optimized Syk siRNAs in FcepsilonRI-activated RBL-2H3 basophilic cells (English)

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14 September 2017

Michael P Sanderson

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14 September 2017

Stephen J Gelling

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2

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14 September 2017

Jörg F Rippmann

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3

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14 September 2017

Andreas Schnapp

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4

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14 September 2017

14 December 2009

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14 September 2017

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14 September 2017

262

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14 September 2017

1

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14 September 2017

28-34

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Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas.

14 September 2017

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12 December 2020

NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling

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12 December 2020

Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells

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12 December 2020

Treatment of rheumatoid arthritis with a Syk kinase inhibitor: a twelve-week, randomized, placebo-controlled trial

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12 December 2020

The many faces of ITAMs.

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12 December 2020

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

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12 December 2020

Nasal delivery of siRNA

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12 December 2020

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

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12 December 2020

Antisense oligonucleotides to Syk kinase: a novel therapeutic approach for respiratory disorders.

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12 December 2020

The orally available spleen tyrosine kinase inhibitor 2-[7-(3,4-dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino]nicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents

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12 December 2020

Respiratory syncytial virus infection in Fischer 344 rats is attenuated by short interfering RNA against the RSV-NS1 gene

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12 December 2020

Aerosolized Syk antisense suppresses Syk expression, mediator release from macrophages, and pulmonary inflammation

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12 December 2020

A unique insert in the linker domain of Syk is necessary for its function in immunoreceptor signalling

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12 December 2020

Physical and functional interaction between p72(syk) and erythropoietin receptor

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12 December 2020

Tyrosine kinase Syk associates with toll-like receptor 4 and regulates signaling in human monocytic cells

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12 December 2020

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

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12 December 2020

Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor

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12 December 2020

Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain

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12 December 2020

Tissue-specific and inducer-specific differential induction of ISG56 and ISG54 in mice.

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12 December 2020

Protection against lethal influenza virus challenge by RNA interference in vivo.

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12 December 2020

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment

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12 December 2020

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

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12 December 2020

RNase L: Its biological roles and regulation

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12 December 2020

A novel Syk-dependent mechanism of platelet activation by the C-type lectin receptor CLEC-2.

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12 December 2020

Antisense- and RNA interference-based therapeutic strategies in allergy.

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12 December 2020

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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12 December 2020

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

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12 December 2020

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice

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12 December 2020

Inhibition of respiratory viruses by nasally administered siRNA.

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12 December 2020

Synthetic shRNAs as potent RNAi triggers.

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12 December 2020

Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.

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12 December 2020

Inhalable siRNA: potential as a therapeutic agent in the lungs

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12 December 2020

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

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12 December 2020

Spleen tyrosine kinase: a novel target for therapeutic intervention of rheumatoid arthritis

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12 December 2020

Targeting Syk as a treatment for allergic and autoimmune disorders

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12 December 2020

Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase

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12 December 2020

Delivering small interfering RNA for novel therapeutics

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12 December 2020

Spleen tyrosine kinase (Syk) as a novel target for allergic asthma and rhinitis

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12 December 2020

Activation of the interferon system by short-interfering RNAs

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12 December 2020

Mast cell inhibitor R112 is well tolerated and affects prostaglandin D2 but not other mediators, symptoms, or nasal volumes in a nasal challenge model of allergic rhinitis

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12 December 2020

Inhibition of mast cell Fc epsilon R1-mediated signaling and effector function by the Syk-selective inhibitor, piceatannol.

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12 December 2020

Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

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12 December 2020

An orally bioavailable spleen tyrosine kinase inhibitor delays disease progression and prolongs survival in murine lupus

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12 December 2020

Novel functions of proteins encoded by viral stress-inducible genes

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12 December 2020

Modulating the expression of disease genes with RNA-based therapy.

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12 December 2020

Small interfering RNA therapy in cancer: mechanism, potential targets, and clinical applications

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12 December 2020

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

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12 December 2020

10.1016/J.CELLIMM.2009.12.004

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DOI

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14 September 2017

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