Non-CDK-bound p27 (p27(NCDK)) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways (Q39758775)

14 September 2017

Non-CDK-bound p27 (p27(NCDK)) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways (English)

1 reference

14 September 2017

2

1 reference

14 September 2017

5

1 reference

14 September 2017

Mia A Björklund

1

1 reference

14 September 2017

Karita Peltonen

3

1 reference

14 September 2017

Benoît Viollet

4

1 reference

14 September 2017

Arja M Band

6

1 reference

14 September 2017

Marikki Laiho

7

1 reference

14 September 2017

language of work or name

English

0 references

publication date

28 December 2009

1 reference

Experimental Cell Research

14 September 2017

1 reference

14 September 2017

316

1 reference

14 September 2017

5

1 reference

14 September 2017

762-774

1 reference

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

14 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

New functional activities for the p21 family of CDK inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

CDK inhibitors: positive and negative regulators of G1-phase progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

p27Kip1 and p21Cip1 Are Not Required for the Formation of Active D Cyclin-cdk4 Complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Cdc2-cyclin E complexes regulate the G1/S phase transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

ErbB2/Neu-induced, cyclin D1-dependent transformation is accelerated in p27-haploinsufficient mammary epithelial cells but impaired in p27-null cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

p27Kip1 modulates cell migration through the regulation of RhoA activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Cyclin E-CDK2 is a regulator of p27Kip1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Accumulation of a form of p27(Kip1) not associated with Cdk-cyclin complexes in transforming growth factor-beta-arrested Mv1Lu cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Reversible arrest of growth in G1 of an established fibroblast line (3T3)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Adenovirus-mediated p53 gene delivery inhibits 9L glioma growth in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Peptide inhibition of catalytic and noncatalytic activities of matrix metalloproteinase-9 blocks tumor cell migration and invasion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Hepatocyte growth factor releases mink epithelial cells from transforming growth factor beta1-induced growth arrest by restoring Cdk6 expression and cyclin E-associated Cdk2 activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Smad transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Lkb1 is required for TGFbeta-mediated myofibroblast differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

mTOR-raptor binds and activates SGK1 to regulate p27 phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

Subcellular Localization and Protein Levels of Cyclin-Dependent Kinase Inhibitor p27 Independently Predict for Survival in Epithelial Ovarian Cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2009.12.014

10.1016/J.YEXCR.2009.12.014

7 January 2021

Identifiers

DOI

1 reference

14 September 2017

1 reference