Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival (Q39761203)

14 September 2017

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival (English)

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14 September 2017

4

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14 September 2017

Jeffrey Eastham-Anderson

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object named as

Jeffrey Eastham-Anderson

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14 September 2017

Martin Schwickart

1

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14 September 2017

Xiaodong Huang

2

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14 September 2017

Jennie R Lill

3

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14 September 2017

Ronald Ferrando

5

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14 September 2017

Dorothy M French

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14 September 2017

Heather Maecker

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14 September 2017

Karen O'Rourke

8

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14 September 2017

Fernando Bazan

9

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14 September 2017

Peng Yue

11

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14 September 2017

David Dornan

12

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14 September 2017

David C S Huang

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14 September 2017

Vishva M Dixit

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14 September 2017

language of work or name

English

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publication date

20 December 2009

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14 September 2017

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14 September 2017

463

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7277

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103-107

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https://scigraph.springernature.com/pub.10.1038/nature08646

14 September 2017

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cites work

Automated selection of DAB-labeled tissue for immunohistochemical quantification.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNATURE08646

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

21 January 2018

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12 December 2020

Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

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12 December 2020

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12 December 2020

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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12 December 2020

Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with In vitro and In vivo chemoresponses.

1 reference

12 December 2020

Interleukin-3 stimulation of mcl-1 gene transcription involves activation of the PU.1 transcription factor through a p38 mitogen-activated protein kinase-dependent pathway.

1 reference

12 December 2020

Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse.

1 reference

12 December 2020

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

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12 December 2020

The Hallmarks of Cancer

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12 December 2020

The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X

1 reference

12 December 2020

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

1 reference

12 December 2020

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

1 reference

12 December 2020

Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death.

1 reference

12 December 2020

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

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12 December 2020

Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

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12 December 2020

Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1.

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12 December 2020

Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies

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12 December 2020

The molecular classification of multiple myeloma

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12 December 2020

Cloning and expression analysis of a novel mouse gene with sequence similarity to the Drosophila fat facets gene.

1 reference

12 December 2020

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

1 reference

12 December 2020

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

1 reference

12 December 2020

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

12 December 2020

A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells

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12 December 2020

Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival.

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12 December 2020

Unique biology of Mcl-1: therapeutic opportunities in cancer

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12 December 2020

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

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12 December 2020

High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

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12 December 2020

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

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12 December 2020

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

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12 December 2020

Increased expression of Mcl-1 is required for protection against serum starvation in phosphatase and tensin homologue on chromosome 10 null mouse embryonic fibroblasts, but repression of Bim is favored in human glioblastomas

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12 December 2020

Identifiers

DOI

10.1038/NATURE08646

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Dimensions Publication ID

14 September 2017

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