Plk1 regulates liver tumor cell death by phosphorylation of TAp63. (Q39814328)

14 September 2017

title

Plk1 regulates liver tumor cell death by phosphorylation of TAp63. (English)

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14 September 2017

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6

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14 September 2017

S Komatsu

1

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14 September 2017

H Takenobu

2

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14 September 2017

T Ozaki

3

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14 September 2017

K Ando

4

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14 September 2017

N Koida

5

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14 September 2017

T Ichikawa

7

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14 September 2017

T Hishiki

8

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14 September 2017

T Chiba

9

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14 September 2017

A Iwama

10

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14 September 2017

H Yoshida

11

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14 September 2017

N Ohnuma

12

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14 September 2017

A Nakagawara

13

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14 September 2017

T Kamijo

14

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14 September 2017

language of work or name

English

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publication date

10 August 2009

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14 September 2017

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14 September 2017

volume

28

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14 September 2017

issue

41

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14 September 2017

page(s)

3631-3641

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p73 and p63: why do we still need them?

14 September 2017

cites work

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https://api.crossref.org/works/10.1038%2FONC.2009.216

TAp63 and DeltaNp63 in cancer and epidermal development

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https://api.crossref.org/works/10.1038%2FONC.2009.216

The protein stability and transcriptional activity of p63alpha are regulated by SUMO-1 conjugation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Altered sumoylation of p63alpha contributes to the split-hand/foot malformation phenotype

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Loss of p63 expression is associated with tumor progression in bladder cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Ultraviolet radiation induces phosphorylation and ubiquitin-mediated degradation of DeltaNp63alpha

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Cancer stem cells: Models, mechanisms and implications for improved treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Prognostic prediction and treatment strategy in hepatocellular carcinoma.

31 March 2020

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p63 is upstream of IKK alpha in epidermal development

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties

31 March 2020

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Polo-like kinase 1: target and regulator of anaphase-promoting complex/cyclosome-dependent proteolysis

31 March 2020

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p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation

31 March 2020

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p63 is the molecular switch for initiation of an epithelial stratification program

31 March 2020

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p53, the cellular gatekeeper for growth and division

31 March 2020

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Polo-like kinase 1 is essential for early embryonic development and tumor suppression

31 March 2020

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Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta

31 March 2020

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p63 is a p53 homologue required for limb and epidermal morphogenesis

31 March 2020

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Hepatocellular carcinoma: from gene to public health.

31 March 2020

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Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate.

31 March 2020

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Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

31 March 2020

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Estimating the world cancer burden: Globocan 2000.

31 March 2020

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The expression of TA and DeltaNp63 are regulated by different mechanisms in liver cells.

31 March 2020

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p63 mediates survival in squamous cell carcinoma by suppression of p73-dependent apoptosis

31 March 2020

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The p53 family member genes are involved in the Notch signal pathway

31 March 2020

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Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis.

31 March 2020

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Polo-like kinase-1 is a target of the DNA damage checkpoint

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Targeting polo-like kinase 1 for cancer therapy.

31 March 2020

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p63 protects the female germ line during meiotic arrest

31 March 2020

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Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM- or ATR-dependent fashion.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Live or let die: the cell's response to p53

31 March 2020

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The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.216

Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.216

Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.216

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.216

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.216

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.216

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Dimensions Publication ID

14 September 2017

1044633569

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