Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response (Q39822052)

14 September 2017

Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response (English)

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14 September 2017

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Hiroshi Nishida

1

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14 September 2017

Naoto Tatewaki

2

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14 September 2017

Yuki Nakajima

3

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14 September 2017

Taku Magara

4

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14 September 2017

Kam Ming Ko

5

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14 September 2017

Yasuo Hamamori

6

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14 September 2017

Tetsuya Konishi

7

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14 September 2017

22 July 2009

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full work available at URL

14 September 2017

https://academic.oup.com/nar/article-pdf/37/17/5678/4910074/gkp593.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1093/nar/gkp593?email=unpaywall_01@example.com

published in

Nucleic Acids Research

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14 September 2017

37

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14 September 2017

17

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14 September 2017

5678-5689

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https://api.unpaywall.org/v2/10.1093/nar/gkp593?email=unpaywall_01@example.com

14 September 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

based on heuristic

inferred from online access status

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MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

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Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

22 September 2017

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

22 September 2017

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ATR and ATRIP: partners in checkpoint signaling

22 September 2017

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Cell cycle checkpoint signaling through the ATM and ATR kinases

22 September 2017

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The many substrates and functions of ATM

22 September 2017

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ATM and ATR: networking cellular responses to DNA damage

22 September 2017

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ATR disruption leads to chromosomal fragmentation and early embryonic lethality

22 September 2017

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A role for ATR in the DNA damage-induced phosphorylation of p53

22 September 2017

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22 September 2017

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

22 September 2017

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Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control

22 September 2017

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DNA damage induces phosphorylation of the amino terminus of p53

22 September 2017

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Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay.

22 September 2017

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22 September 2017

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22 September 2017

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S phase and G2 arrests induced by topoisomerase I poisons are dependent on ATR kinase function

22 September 2017

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Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents

25 September 2017

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The Ataxia telangiectasia gene product is required for oxidative stress-induced G1 and G2 checkpoint function in human fibroblasts

25 September 2017

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Defective control of apoptosis and mitotic spindle checkpoint in heterozygous carriers of ATM mutations

25 September 2017

1 reference

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Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

25 September 2017

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Pharmacological actions and clinical use of fructus schizandrae

25 September 2017

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How ATR turns on: TopBP1 goes on ATRIP with ATR.

17 June 2018

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DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system

20 August 2018

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Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors.

20 August 2018

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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

20 August 2018

1 reference

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Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity

20 August 2018

1 reference

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ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19625493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Flow cytometry after bromodeoxyuridine labeling to measure S and G2+M phase durations plus doubling times in vitro and in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19625493

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKP593

1 reference

14 September 2017

1 reference

14 September 2017

1 reference