Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells (Q39893311)

15 September 2017

Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells (English)

1 reference

15 September 2017

1 reference

6

P L Olive

1 reference

15 September 2017

1

J P Banáth

1 reference

15 September 2017

C A Bañuelos

2

1 reference

15 September 2017

D Klokov

series ordinal

3

1 reference

15 September 2017

S M MacPhail

series ordinal

4

1 reference

15 September 2017

P M Lansdorp

series ordinal

5

1 reference

15 September 2017

language of work or name

English

0 references

publication date

24 December 2008

1 reference

Experimental Cell Research

15 September 2017

1 reference

15 September 2017

315

1 reference

15 September 2017

8

1 reference

15 September 2017

1505-1520

1 reference

Chromatin in pluripotent embryonic stem cells and differentiation

15 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Physical plasticity of the nucleus in stem cell differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Visualizing chromatin dynamics in interphase nuclei.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Epigenetic signatures of stem-cell identity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Human embryonic stem cells have enhanced repair of multiple forms of DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA repair defects in stem cell function and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

An ageing question: do embryonic stem cells protect their genomes?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Induction and rejoining of radiation-induced DNA single-strand breaks: "tail moment" as a function of position in the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Endogenous expression of phosphorylated histone H2AX in tumors in relation to DNA double-strand breaks and genomic instability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Melanoma cells express elevated levels of phosphorylated histone H2AX foci

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Quantitative analysis reveals asynchronous and more than DSB-associated histone H2AX phosphorylation after exposure to ionizing radiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Heterochromatin is refractory to gamma-H2AX modification in yeast and mammals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Radiosensitization by the histone deacetylase inhibitor PCI-24781.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Global chromatin compaction limits the strength of the DNA damage response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA double-strand breaks and gamma-H2AX signaling in the testis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Dynamic change of histone H2AX phosphorylation independent of ATM and DNA-PK in mouse skin in situ

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Fibroblast growth factor receptor 3 is a negative regulator of bone growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Meta-analysis of differentiating mouse embryonic stem cell gene expression kinetics reveals early change of a small gene set.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Glycoconjugate expression during embryogenesis and its biological significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

The comet assay: a method to measure DNA damage in individual cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Inhibition of DNA synthesis by nitroheterocycles. II. Mechanisms of cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA precipitation assay: a rapid and simple method for detecting DNA damage in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Visualization of DNA loops in nucleoids from HeLa cells: assays for DNA damage and repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Osmotically driven radial diffusion of single-stranded DNA fragments on an agarose bed as a convenient measure of DNA strand scission

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Megabase chromatin domains involved in DNA double-strand breaks in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Cytometric assessment of DNA damage in relation to cell cycle phase and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Inhibition of the ATR/Chk1 pathway induces a p38-dependent S-phase delay in mouse embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Caffeine inhibits checkpoint responses without inhibiting the ataxia-telangiectasia-mutated (ATM) and ATM- and Rad3-related (ATR) protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Interaction of human rad51 recombination protein with single-stranded DNA binding protein, RPA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA strand breakage and DNA structure influence staining with propidium iodide using the alkaline comet assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA replication in mammalian cells. Altered patterns of initiation during inhibition of protein synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Spatio-temporal organization of DNA replication in murine embryonic stem, primary, and immortalized cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Supercoiled loops and eucaryotic DNA replicaton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Mitotic remodeling of the replicon and chromosome structure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Techniques to measure DNA single-strand breaks in cells: a review

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

DNA repair in murine embryonic stem cells and differentiated cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Activation of DNA damage response signaling in mouse embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Rad51 accumulation at sites of DNA damage and in postreplicative chromatin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Analysis of ionizing radiation-induced foci of DNA damage repair proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

BRCA2-dependent and independent formation of RAD51 nuclear foci.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Modification of the Comet assay for the detection of DNA strand breaks in extremely small tissue samples

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Reversibility of the low-salt transition of chromatin core particles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Alkali-labile sites are prevalent in kidney tissue DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Abundant alkali-sensitive sites in DNA of human and mouse sperm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Structure of human sperm DNA and background damage, analysed by in situ enzymatic treatment and digital image analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Hemoglobin and hemin induce DNA damage in human colon tumor cells HT29 clone 19A and in primary human colonocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Pluripotent stem cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Embryonic stem cells: similarities and differences between human and murine embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

New cell lines from mouse epiblast share defining features with human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Derivation of pluripotent epiblast stem cells from mammalian embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

Advances in cell separation: recent developments in counterflow centrifugal elutriation and continuous flow cell separation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.12.007

10.1016/J.YEXCR.2008.12.007

7 January 2021

Identifiers

DOI

1 reference

15 September 2017

1 reference