Anticytokine therapy for osteoarthritis: evidence to date (Q39906208)

15 September 2017

Anticytokine therapy for osteoarthritis: evidence to date (English)

1 reference

15 September 2017

0 references

Charles J Malemud

1

1 reference

15 September 2017

1 February 2010

1 reference

15 September 2017

1 reference

15 September 2017

27

1 reference

15 September 2017

2

1 reference

15 September 2017

95-115

1 reference

https://scigraph.springernature.com/pub.10.2165/11319950-000000000-00000

15 September 2017

0 references

cites work

Interleukin-6 and tumour necrosis factor in synovial fluid from horses with carpal joint pathology.

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

Glucosamine and chondroitin for osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

Function of neurotrophic factors beyond the nervous system: inflammation and autoimmune demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

Aggrecanase and aggrecan degradation in osteoarthritis: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

Reduced Incidence and Severity of Collagen-Induced Arthritis in Mice Lacking IL-18

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F11319950-000000000-00000

Role of the growth hormone/insulin-like growth factor-1 paracrine axis in rheumatic diseases

21 January 2018

1 reference

12 December 2020

Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage.

1 reference

12 December 2020

The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models

1 reference

12 December 2020

Interleukin-6 gene polymorphism and risk of osteoarthritis of the hip: a case-control study

1 reference

12 December 2020

The complex pathology of osteoarthritis: even mitochondria are involved

1 reference

12 December 2020

A proinflammatory role for IL-18 in rheumatoid arthritis

1 reference

12 December 2020

Interleukin-18 induces apoptosis in human articular chondrocytes.

1 reference

12 December 2020

Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study

1 reference

12 December 2020

Interleukin-1beta and interleukin-6 disturb the antioxidant enzyme system in bovine chondrocytes: a possible explanation for oxidative stress generation

1 reference

12 December 2020

Cytokine targeting in osteoarthritis

1 reference

12 December 2020

Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies

1 reference

12 December 2020

Persistence of interleukin 7 activity and levels on tumour necrosis factor alpha blockade in patients with rheumatoid arthritis

1 reference

12 December 2020

Relation between interleukin-18 and PGE2 in synovial fluid of osteoarthritis: a potential therapeutic target of cartilage degradation

1 reference

12 December 2020

Transforming growth factor-{beta}-inducible phosphorylation of Smad3

1 reference

12 December 2020

Homeostasis of naive and memory T cells

1 reference

12 December 2020

A randomized, multicentre, double-blind, parallel-group study to assess the adverse event-related discontinuation rate with celecoxib and diclofenac in elderly patients with osteoarthritis

1 reference

12 December 2020

Early lymphocyte activation in the synovial microenvironment in patients with osteoarthritis: comparison with rheumatoid arthritis patients and healthy controls

1 reference

12 December 2020

Is interleukin-1 a good target for therapeutic intervention in intervertebral disc degeneration: lessons from the osteoarthritic experience

1 reference

12 December 2020

Metabolic disturbances and synovial joint responses in osteoarthritis

1 reference

12 December 2020

Reduced transforming growth factor-beta signaling in cartilage of old mice: role in impaired repair capacity

1 reference

12 December 2020

Interleukin-4 antagonizes oncostatin M and transforming growth factor beta-induced responses in articular chondrocytes

1 reference

12 December 2020

Interleukin-7: from bench to clinic

1 reference

12 December 2020

Mechanisms for asporin function and regulation in articular cartilage

1 reference

12 December 2020

The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.

1 reference

12 December 2020

Signaling pathways implicated in oncostatin M-induced aggrecanase-1 and matrix metalloproteinase-13 expression in human articular chondrocytes

1 reference

12 December 2020

Interleukin-17, a regulator of angiogenic factor release by synovial fibroblasts

1 reference

12 December 2020

Human articular chondrocytes produce IL-7 and respond to IL-7 with increased production of matrix metalloproteinase-13.

1 reference

12 December 2020

Inhibitors of stress-activated protein/mitogen-activated protein kinase pathways

1 reference

12 December 2020

A new player in cartilage homeostasis: adiponectin induces nitric oxide synthase type II and pro-inflammatory cytokines in chondrocytes.

1 reference

12 December 2020

Chondroprotective drugs in degenerative joint diseases

1 reference

12 December 2020

Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis

1 reference

12 December 2020

Defining the roles of inflammatory and anabolic cytokines in cartilage metabolism

1 reference

12 December 2020

Intraarticular injection of anakinra in osteoarthritis of the knee: a multicenter, randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

A review of the effects of insulin-like growth factor and platelet derived growth factor on in vivo cartilage healing and repair

1 reference

12 December 2020

Oncostatin M, a multifunctional cytokine

1 reference

12 December 2020

Enhanced expression of interleukin-6, matrix metalloproteinase-13, and receptor activator of NF-kappaB ligand in cells derived from osteoarthritic subchondral bone.

1 reference

12 December 2020

Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489].

1 reference

12 December 2020

Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.

1 reference

12 December 2020

The interleukin 1beta pathway in the pathogenesis of osteoarthritis

1 reference

12 December 2020

Matrix metalloproteinases: role in arthritis

1 reference

12 December 2020

A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes

1 reference

12 December 2020

TNF-alpha convertase enzyme from human arthritis-affected cartilage: isolation of cDNA by differential display, expression of the active enzyme, and regulation of TNF-alpha

1 reference

12 December 2020

In vitro model for the analysis of synovial fibroblast-mediated degradation of intact cartilage

1 reference

12 December 2020

Leukemia inhibitory factor is expressed in cartilage and synovium and can contribute to the pathogenesis of arthritis

1 reference

12 December 2020

The algofunctional indices for hip and knee osteoarthritis

1 reference

12 December 2020

T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis

1 reference

12 December 2020

The IL-1 family and inflammatory diseases.

1 reference

12 December 2020

Oncostatin M in combination with tumour necrosis factor {alpha} induces a chondrocyte membrane associated aggrecanase that is distinct from ADAMTS aggrecanase-1 or -2.

1 reference

12 December 2020

Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1beta.

1 reference

12 December 2020

Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis

1 reference

12 December 2020

Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function

1 reference

12 December 2020

In vivo osteoarthritis target validation utilizing genetically-modified mice

1 reference

12 December 2020

ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage

1 reference

12 December 2020

The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis

1 reference

12 December 2020

Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

1 reference

12 December 2020

Inflammation induction of Dickkopf-1 mediates chondrocyte apoptosis in osteoarthritic joint.

1 reference

12 December 2020

Osteoblasts from the sclerotic subchondral bone downregulate aggrecan but upregulate metalloproteinases expression by chondrocytes. This effect is mimicked by interleukin-6, -1beta and oncostatin M pre-treated non-sclerotic osteoblasts.

1 reference

12 December 2020

Efficacy of intraarticular infliximab in patients with chronic or recurrent gonarthritis: a clinical randomized trial.

1 reference

12 December 2020

Cell death in osteoarthritis

1 reference

12 December 2020

Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis

1 reference

12 December 2020

Antigen-induced inflammatory mechanical hypernociception in mice is mediated by IL-18.

1 reference

12 December 2020

Cytokine induced metalloproteinase expression and activity does not correlate with focal susceptibility of articular cartilage to degeneration.

1 reference

12 December 2020

Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage

1 reference

12 December 2020

Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor).

1 reference

12 December 2020

Cartilage destruction by matrix degradation products

1 reference

12 December 2020

Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes

1 reference

12 December 2020

The CO-releasing molecule CORM-2 is a novel regulator of the inflammatory process in osteoarthritic chondrocytes

1 reference

12 December 2020

Pathophysiological roles for IL-18 in inflammatory arthritis

1 reference

12 December 2020

Benzo[d]isothiazol-3-yl-benzamidines: a class of protective agents on culture of human cartilage and chondrocytes stimulated by IL-1beta

1 reference

12 December 2020

Activation of cartilage matrix metalloproteinases by activated protein C.

1 reference

12 December 2020

Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis

1 reference

12 December 2020

VEGF production by osteoarthritic chondrocytes cultured in micromass and stimulated by IL-17 and TNF-alpha

1 reference

12 December 2020

1 reference

12 December 2020

Cell death and apoptosis in osteoarthritic cartilage

1 reference

12 December 2020

The angiogenic pathway ?vascular endothelial growth factor/flk-1(KDR)-receptor? in rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Osteoblasts and stromal cells isolated from femora in rheumatoid arthritis (RA) and osteoarthritis (OA) patients express IL-11, leukaemia inhibitory factor and oncostatin M.

1 reference

12 December 2020

Interleukin-18 regulates both Th1 and Th2 responses

1 reference

12 December 2020

Tumor necrosis factor alpha drugs in rheumatoid arthritis: systematic review and metaanalysis of efficacy and safety

1 reference

12 December 2020

Characterization of an ADAMTS-5-mediated cleavage site in aggrecan in OSM-stimulated bovine cartilage.

1 reference

12 December 2020

Mechanism of proteoglycan aggregate degradation in cartilage stimulated with oncostatin M.

1 reference

12 December 2020

Clinical review of chondroitin sulfate in osteoarthritis

1 reference

12 December 2020

A prospective, randomized, double-blind, placebo controlled study to evaluate the efficacy of intraarticular hyaluronic acid for osteoarthritis of the knee

1 reference

12 December 2020

Anti-apoptotic effect of transforming growth factor-beta1 on human articular chondrocytes: role of protein phosphatase 2A.

1 reference

12 December 2020

A randomized, controlled study of a single intra-articular injection of etanercept or glucocorticosteroids in patients with rheumatoid arthritis

1 reference

12 December 2020

Cytokines and anti-cytokines as therapeutics--an update.

1 reference

12 December 2020

Aging, articular cartilage chondrocyte senescence and osteoarthritis

1 reference

12 December 2020

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer

1 reference

12 December 2020

Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes

1 reference

12 December 2020

Inflammatory molecules: a target for treatment of systemic autoimmune diseases

1 reference

12 December 2020

Postmarketing surveillance of serious adverse events associated with the use of rofecoxib from 1999-2002.

1 reference

12 December 2020

Expression and regulation of the osteoarthritis-associated protein asporin

1 reference

12 December 2020

Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

1 reference

12 December 2020

Small molecular weight inhibitors of stress-activated and mitogen-activated protein kinases

1 reference

12 December 2020

Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes.

1 reference

12 December 2020

Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis

1 reference

12 December 2020

Anticytokine therapy for osteoarthritis

1 reference

12 December 2020

Connective tissue growth factor/CCN2 overexpression in mouse synovial lining results in transient fibrosis and cartilage damage

1 reference

12 December 2020

Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice.

1 reference

12 December 2020

Inducible nitric oxide synthase activation by interleukin-17.

1 reference

12 December 2020

Methylation status of a single CpG site in the IL6 promoter is related to IL6 messenger RNA levels and rheumatoid arthritis.

1 reference

12 December 2020

Design strategies for the identification of MMP-13 and Tace inhibitors

1 reference

12 December 2020

Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism

1 reference

12 December 2020

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis

1 reference

12 December 2020

The design and synthesis of aryl hydroxamic acid inhibitors of MMPs and TACE.

1 reference

12 December 2020

Developments in the scientific understanding of osteoarthritis

1 reference

12 December 2020

TCR-independent proliferation and differentiation of human CD4+ T cell subsets induced by cytokines

1 reference

12 December 2020

Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease

1 reference

12 December 2020

The roles of interleukin-18 in collagen-induced arthritis in the BB rat.

1 reference

12 December 2020

Treating knee osteoarthritis with intra-articular hyaluronans

1 reference

12 December 2020

The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial

1 reference

12 December 2020

Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study

1 reference

12 December 2020

Male IL-6 gene knock out mice developed more advanced osteoarthritis upon aging

1 reference

12 December 2020

The role of T cells in the pathogenesis of osteoarthritis

1 reference

12 December 2020

Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy

1 reference

12 December 2020

Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs

1 reference

12 December 2020

Differential Toll-like receptor-dependent collagenase expression in chondrocytes

1 reference

12 December 2020

The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.

1 reference

12 December 2020

Inhibition of COX-2 by celecoxib in the canine groove model of osteoarthritis

1 reference

12 December 2020

Leukaemia inhibitory factor is identical to the myeloid growth factor human interleukin for DA cells

1 reference

12 December 2020

Phenotypic characterization of inflammatory cells from osteoarthritic synovium and synovial fluids.

1 reference

12 December 2020

Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction

1 reference

12 December 2020

MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

1 reference

12 December 2020

Implication of interleukin 18 in production of matrix metalloproteinases in articular chondrocytes in arthritis: direct effect on chondrocytes may not be pivotal

1 reference

12 December 2020

Interleukin-1 in combination with oncostatin M up-regulates multiple genes in chondrocytes: implications for cartilage destruction and repair

1 reference

12 December 2020

Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis

1 reference

12 December 2020

Role of CCN2/CTGF/Hcs24 in bone growth

1 reference

12 December 2020

A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis

1 reference

12 December 2020

A high interleukin 1 receptor antagonist/IL-1beta ratio occurs naturally in knee osteoarthritis

1 reference

12 December 2020

Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage

1 reference

12 December 2020

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage

1 reference

12 December 2020

Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis.

1 reference

12 December 2020

Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study

1 reference

12 December 2020

Cytokines as therapeutic targets for osteoarthritis

1 reference

12 December 2020

Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes.

1 reference

12 December 2020

The role of cytokines in osteoarthritis pathophysiology

1 reference

12 December 2020

Treatment of osteoarthritis with anakinra

1 reference

12 December 2020

Abnormal transforming growth factor-beta expression in mesenchymal stem cells from patients with osteoarthritis

1 reference

12 December 2020

Differential effects of IL-8, LIF (pro-inflammatory) and IL-11 (anti-inflammatory) on TNF-alpha-induced PGE(2)release and on signalling pathways in human OA synovial fibroblasts

1 reference

12 December 2020

A prospective study of autologous chondrocyte implantation in patients with failed prior treatment for articular cartilage defect of the knee: results of the Study of the Treatment of Articular Repair (STAR) clinical trial

1 reference

12 December 2020

Epigallocatechin-3-gallate selectively inhibits interleukin-1beta-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes

1 reference

12 December 2020

Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes.

1 reference

12 December 2020

Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro

1 reference

12 December 2020

Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis

1 reference

12 December 2020

Elevated IL-6 levels in the synovial fluid of osteoarthritis patients stem from plasma cells.

1 reference

12 December 2020

Differences in signaling pathways by IL-1beta and IL-18.

1 reference

12 December 2020

Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13

1 reference

12 December 2020

Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism

1 reference

12 December 2020

Expression profiling of select cytokines in canine osteoarthritis tissues

1 reference

12 December 2020

Role of bone in osteoarthritis pathogenesis

1 reference

12 December 2020

The regulation of the ADAMTS4 and ADAMTS5 aggrecanases in osteoarthritis: a review

1 reference

12 December 2020

Interleukin 17 synergises with tumour necrosis factor alpha to induce cartilage destruction in vitro

1 reference

12 December 2020

Contribution of interleukin 17 to human cartilage degradation and synovial inflammation in osteoarthritis

1 reference

12 December 2020

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

1 reference

12 December 2020

Inflammatory signaling in cartilage: MAPK and NF-kappaB pathways in chondrocytes and the use of inhibitors for research into pathogenesis and therapy of osteoarthritis

1 reference

12 December 2020

Expression of platelet-derived growth factors C and D in the synovial membrane of patients with rheumatoid arthritis and osteoarthritis.

1 reference

12 December 2020

Selective COX-2 inhibition is favorable to human early and late-stage osteoarthritic cartilage: a human in vitro study

1 reference

12 December 2020

Evaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritis

1 reference

12 December 2020

Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts

1 reference

12 December 2020

Ten years in the life of an enzyme: the story of the human MMP-13 (collagenase-3).

1 reference

12 December 2020

TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7.

1 reference

12 December 2020

Leptin: a metabolic hormone that functions like a proinflammatory adipokine.

1 reference

12 December 2020

Oncostatin M in combination with tumor necrosis factor alpha induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo.

1 reference

12 December 2020

Role of interleukin-7 in degenerative and inflammatory joint diseases

1 reference

12 December 2020

Synovial fluid levels of tumor necrosis factor alpha and oncostatin M correlate with levels of markers of the degradation of crosslinked collagen and cartilage aggrecan in rheumatoid arthritis but not in osteoarthritis

1 reference

12 December 2020

Drug insight: aggrecanases as therapeutic targets for osteoarthritis.

1 reference

12 December 2020

Enhanced production of MMP-1, MMP-3, MMP-13, and RANTES by interaction of chondrocytes with autologous T cells.

1 reference

12 December 2020

Etiopathogenesis of osteoarthritis

1 reference

12 December 2020

Failure of serum transforming growth factor-beta (TGF-beta1) as a biomarker of radiographic osteoarthritis at the knee and hip: a cross-sectional analysis in the Johnston County Osteoarthritis Project.

1 reference

12 December 2020

The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis

1 reference

12 December 2020

Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated NF-kappaBp65-specific siRNA.

1 reference

12 December 2020

Discoidin domain receptor 2 mediates the collagen II-dependent release of interleukin-6 in primary human chondrocytes.

1 reference

12 December 2020

IL-1beta induction of IL-6 and LIF in normal articular human chondrocytes involves the ERK, p38 and NFkappaB signaling pathways

1 reference

12 December 2020

Mesenchymal stem cells in arthritic diseases

1 reference

12 December 2020

Is IL-1 a good therapeutic target in the treatment of arthritis?

1 reference

12 December 2020

Leukemia-inhibitory factor-neuroimmune modulator of endocrine function

1 reference

12 December 2020

Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9.

1 reference

12 December 2020

Autologous interleukin-1 receptor antagonist improves function and symptoms in osteoarthritis when compared to placebo in a prospective randomized controlled trial

1 reference

12 December 2020

The induction of cell death in human osteoarthritis chondrocytes by nitric oxide is related to the production of prostaglandin E2 via the induction of cyclooxygenase-2

1 reference

12 December 2020

Pharmacological therapy of osteoarthritis

1 reference

12 December 2020

Pro-inflammatory cytokine-induced SAPK/MAPK and JAK/STAT in rheumatoid arthritis and the new anti-depression drugs

1 reference

12 December 2020

Efficacy of rofecoxib, celecoxib, and acetaminophen in patients with osteoarthritis of the knee. A combined analysis of the VACT studies

1 reference

12 December 2020

The Contribution of Genes to Osteoarthritis

1 reference

12 December 2020

Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter

1 reference

12 December 2020

Osteoarthritis: pathobiology-targets and ways for therapeutic intervention

1 reference

12 December 2020

(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase

1 reference

12 December 2020

10.2165/11319950-000000000-00000

Identifiers

DOI

1 reference

PubMed ID

20104937

Dimensions Publication ID

15 September 2017

0 references

1 reference

PubMed ID

20104937