The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells (Q39944686)

15 September 2017

The atypical Rho GTPase RhoBTB2 is required for expression of the chemokine CXCL14 in normal and cancerous epithelial cells (English)

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15 September 2017

5

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15 September 2017

R Mitter

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author name string

C M McKinnon

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1

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15 September 2017

K A Lygoe

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2

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15 September 2017

L Skelton

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3

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15 September 2017

language of work or name

English

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publication date

1 September 2008

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15 September 2017

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15 September 2017

27

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54

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15 September 2017

6856-6865

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https://scigraph.springernature.com/pub.10.1038/onc.2008.317

15 September 2017

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Identification of a candidate tumor suppressor gene RHOBTB1 located at a novel allelic loss region 10q21 in head and neck cancer

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DBC2 is essential for transporting vesicular stomatitis virus glycoprotein

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Genomic analysis of metastasis reveals an essential role for RhoC

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High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

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In vivo expression of the novel CXC chemokine BRAK in normal and cancerous human tissue

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DBC2, a candidate for a tumor suppressor gene involved in breast cancer

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Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells

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Exploration, normalization, and summaries of high density oligonucleotide array probe level data

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POZ for effect--POZ-ZF transcription factors in cancer and development

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Mutation analysis of the 8p candidate tumour suppressor genes DBC2 (RHOBTB2) and LZTS1 in bladder cancer

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Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

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Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development

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Mutation analysis of the DBC2 gene in sporadic and familial breast cancer

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Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6

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Metastatic dissemination of human malignant oral keratinocyte cell lines following orthotopic transplantation reflects response to TGF-beta 1.

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Genomic organization and expression profile of the small GTPases of the RhoBTB family in human and mouse

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Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells

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BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells

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Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo

21 January 2018

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DBC2 significantly influences cell-cycle, apoptosis, cytoskeleton and membrane-trafficking pathways

21 January 2018

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The chemokine CXCL14 (BRAK) stimulates activated NK cell migration: implications for the downregulation of CXCL14 in malignancy.

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RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex

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Cutaneous CXCL14 targets blood precursors to epidermal niches for Langerhans cell differentiation

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Tumor-host immune interactions and dendritic cell dysfunction

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2008.317

1 reference

15 September 2017

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