Heme oxygenase-1 nuclear translocation regulates bortezomibinduced cytotoxicity and mediates genomic instability in myeloma cells (Q39956732)

15 September 2017

Heme oxygenase-1 nuclear translocation regulates bortezomibinduced cytotoxicity and mediates genomic instability in myeloma cells (English)

1 reference

15 September 2017

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8

1 reference

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31 May 2020

Daniele Tibullo

1

1 reference

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31 May 2020

Ignazio Barbagallo

2

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31 May 2020

Cesarina Giallongo

3

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31 May 2020

Alessandra Romano

6

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31 May 2020

Salvatore Saccone

7

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31 May 2020

10

Giovanni Li Volti

1 reference

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31 May 2020

4

Luca Vanella

1 reference

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31 May 2020

Francesco Di Raimondo

9

object named as

Francesco Di Raimondo

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31 May 2020

5

Concetta Conticello

1 reference

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31 May 2020

language of work or name

English

0 references

publication date

22 February 2016

1 reference

15 September 2017

1 reference

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31 May 2020

volume

7

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31 May 2020

issue

20

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31 May 2020

page(s)

28868-28880

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Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

31 May 2020

cites work

1 reference

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Four genes predict high risk of progression from smoldering to symptomatic multiple myeloma (SWOG S0120).

22 September 2017

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Nuclear heme oxygenase-1 (HO-1) modulates subcellular distribution and activation of Nrf2, impacting metabolic and anti-oxidant defenses

22 September 2017

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Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells.

22 September 2017

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Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients

22 September 2017

1 reference

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Heat shock proteins in multiple myeloma

22 September 2017

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Expression level and subcellular localization of heme oxygenase-1 modulates its cytoprotective properties in response to lung injury: a mouse model

22 September 2017

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DNA repair pathways in human multiple myeloma: role in oncogenesis and potential targets for treatment

22 September 2017

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Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.

22 September 2017

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A novel measure of chromosome instability can account for prognostic difference in multiple myeloma

22 September 2017

1 reference

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Genomic instability in multiple myeloma: mechanisms and therapeutic implications

22 September 2017

1 reference

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Nuclear translocation of heme oxygenase-1 confers resistance to imatinib in chronic myeloid leukemia cells

22 September 2017

1 reference

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Potential therapeutic effects of natural heme oxygenase-1 inducers in cardiovascular diseases

22 September 2017

1 reference

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Bortezomib induces heme oxygenase-1 expression in multiple myeloma

22 September 2017

1 reference

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Nuclear localization of heme oxygenase-1 is associated with tumor progression of head and neck squamous cell carcinomas.

22 September 2017

1 reference

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Protocatechuic acid and human disease prevention: biological activities and molecular mechanisms.

22 September 2017

1 reference

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The genetic architecture of multiple myeloma.

22 September 2017

1 reference

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A phase I safety study of enzastaurin plus bortezomib in the treatment of relapsed or refractory multiple myeloma

22 September 2017

1 reference

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Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells

22 September 2017

1 reference

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Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy

22 September 2017

1 reference

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Heme oxygenase-1 and its metabolites affect pancreatic tumor growth in vivo

22 September 2017

1 reference

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Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells

22 September 2017

1 reference

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Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

22 September 2017

1 reference

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Natural heme oxygenase-1 inducers in hepatobiliary function

22 September 2017

1 reference

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Inflammation: its role and interplay in the development of cancer, with special focus on gynecological malignancies

22 September 2017

1 reference

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Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress

22 September 2017

1 reference

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Extensive immunoglobulin production sensitizes myeloma cells for proteasome inhibition.

22 September 2017

1 reference

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Cytokinesis-block micronucleus assay evolves into a "cytome" assay of chromosomal instability, mitotic dysfunction and cell death

22 September 2017

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Regulation of mitotic entry by microcephalin and its overlap with ATR signalling

22 September 2017

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Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

22 September 2017

1 reference

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Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells

22 September 2017

1 reference

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Proteasome inhibitor therapy in multiple myeloma

22 September 2017

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Excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases

22 September 2017

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Immunocytochemical localization and expression of heme oxygenase-1 in primary astroglial cell cultures during differentiation: effect of glutamate

22 September 2017

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A phase 2 study of bortezomib in relapsed, refractory myeloma

22 September 2017

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HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures.

22 September 2017

1 reference

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Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

22 September 2017

1 reference

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The proteasome: a novel target for cancer chemotherapy

22 September 2017

1 reference

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NF-kappa B as a therapeutic target in multiple myeloma

22 September 2017

1 reference

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The in vitro micronucleus technique

22 September 2017

1 reference

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The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase

22 September 2017

1 reference

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Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study

22 September 2017

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Genome-wide siRNA screen for modulators of cell death induced by proteasome inhibitor bortezomib

15 June 2018

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BRIT1/MCPH1 expression in chronic myeloid leukemia and its regulation of the G2/M checkpoint.

15 June 2018

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Hsp60 and heme oxygenase-1 (Hsp32) in acute myocardial infarction.

20 August 2018

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NF-kappaB-inhibited acute myeloid leukemia cells are rescued from apoptosis by heme oxygenase-1 induction

20 August 2018

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Bortezomib and high-dose melphalan as conditioning regimen before autologous stem cell transplantation in patients with de novo multiple myeloma: a phase 2 study of the Intergroupe Francophone du Myelome (IFM).

20 August 2018

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Cytokinesis-block micronucleus cytome assay.

20 August 2018

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Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in inflammation and growth

20 August 2018

1 reference

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Propofol inhibits caspase-3 in astroglial cells: role of heme oxygenase-1.

20 August 2018

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Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

20 August 2018

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20 August 2018

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Guest editorial: understanding the pathogenesis and the evolving treatment paradigm for multiple myeloma in the era of novel agents

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26930712

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Posttranslational and direct integration of heme oxygenase into microsomes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26930712

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TNF-alpha-mediated cell death is attenuated by retrovirus delivery of human heme oxygenase-1 gene into human microvessel endothelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26930712

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.18632/ONCOTARGET.7563

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26930712%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26930712%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

PubMed publication ID

26930712

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26930712%20AND%20SRC:MED&resulttype=core&format=json