The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation (Q39958892)

15 September 2017

The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation (English)

1 reference

15 September 2017

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Marie C Harrisingh

1

1 reference

15 September 2017

Elena Perez-Nadales

2

1 reference

15 September 2017

David B Parkinson

3

1 reference

15 September 2017

Denise S Malcolm

4

1 reference

15 September 2017

Anne W Mudge

5

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15 September 2017

Alison C Lloyd

6

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15 September 2017

language of work or name

English

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publication date

8 July 2004

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15 September 2017

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15 September 2017

23

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15 September 2017

3061-3071

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15 September 2017

15

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Dissecting the contribution of p16(INK4A) and the Rb family to the Ras transformed phenotype.

15 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

EGR2 mutations in inherited neuropathies dominant-negatively inhibit myelin gene expression.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Glial growth factor/neuregulin inhibits Schwann cell myelination and induces demyelination

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Modification of representational difference analysis applied to the isolation of forskolin-regulated genes from Schwann cells

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

NF1 tumor suppressor gene function: narrowing the GAP

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Ras proteins in the control of the cell cycle and cell differentiation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Ras and Rho GTPases: a family reunion

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Neuregulin, a factor with many functions in the life of a schwann cell

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Neurofibromin, the neurofibromatosis type 1 Ras-GAP, is required for appropriate P0 expression and myelination

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Expression of neuregulins and their putative receptors, ErbB2 and ErbB3, is induced during Wallerian degeneration

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Cultured Schwann cells constitutively express the myelin protein P0

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3',5'-monophosphate

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Increasing cAMP attenuates activation of mitogen-activated protein kinase

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Lack of replicative senescence in normal rodent glia

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Differential patterns of ERK and STAT3 phosphorylation after sciatic nerve transection in the rat.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Activation of ErbB2 during wallerian degeneration of sciatic nerve

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Schwann cell development, differentiation and myelination

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Cell number control and timing in animal development: the oligodendrocyte cell lineage.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Calcitonin gene-related peptide promotes Schwann cell proliferation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Inhibition by cAMP of Ras-dependent activation of Raf.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Expression of the protein zero myelin gene in axon-related Schwann cells is linked to basal lamina formation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

SCIP: a glial POU domain gene regulated by cyclic AMP.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

The effects of cAMP on differentiation of cultured Schwann cells: progression from an early phenotype (04+) to a myelin phenotype (P0+, GFAP-, N-CAM-, NGF-receptor-) depends on growth inhibition

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Ras controls growth, survival and differentiation in the Drosophila eye by different thresholds of MAP kinase activity.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Genetics of RAS signaling in C. elegans.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Complexity of EGF receptor signalling revealed in Drosophila.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=514926

Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation

20 August 2018

1 reference

12 December 2020

Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells

1 reference

12 December 2020

Axons regulate Schwann cell expression of the major myelin and NGF receptor genes

1 reference

12 December 2020

Axonal modulation of myelin gene expression in the peripheral nerve

1 reference

12 December 2020

The second messenger, cyclic AMP, is not sufficient for myelin gene induction in the peripheral nervous system

1 reference

12 December 2020

cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways

1 reference

12 December 2020

Retroviral inhibition of cAMP-dependent protein kinase inhibits myelination but not Schwann cell mitosis stimulated by interaction with neurons

1 reference

12 December 2020

Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires PI 3-kinase activity

1 reference

12 December 2020

Neurofibromin, the Neurofibromatosis Type 1 Ras-GAP, Is Required for Appropriate P0 Expression and Myelination

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600309

7 January 2021

inferred from DOI database lookup

The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600309

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7600309

1 reference

release_qjp7aeqervee5plzm4dxdu73za

15 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qjp7aeqervee5plzm4dxdu73za

24 November 2022

mapped directly with Wikidata item

1 reference

15 September 2017

1 reference