Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation. (Q39985677)

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6 January 2020

title

Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation (English)

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6 January 2020

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6 January 2020

author name string

Masaru Harada

1

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6 January 2020

Shinichiro Hanada

2

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6 January 2020

Diana M Toivola

3

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6 January 2020

Nafisa Ghori

4

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6 January 2020

language of work or name

English

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publication date

1 June 2008

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6 January 2020

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6 January 2020

volume

47

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6 January 2020

issue

6

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6 January 2020

page(s)

2026-2035

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Narrative review: protein degradation and human diseases: the ubiquitin connection

6 January 2020

cites work

1 reference

Modification of proteins by ubiquitin and ubiquitin-like proteins

21 January 2018

1 reference

7 January 2021

The proteasome: a suitable antineoplastic target

1 reference

7 January 2021

Proteasome inhibition and its clinical prospects in the treatment of hematologic and solid malignancies

1 reference

7 January 2021

Autophagy and other vacuolar protein degradation mechanisms

1 reference

7 January 2021

Autophagy: in sickness and in health

1 reference

7 January 2021

Autophagy in health and disease: a double-edged sword

1 reference

7 January 2021

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

1 reference

7 January 2021

Proteasome inhibition induces inclusion bodies associated with intermediate filaments and fragmentation of the Golgi apparatus.

1 reference

7 January 2021

Involvement of macroautophagy in the dissolution of neuronal inclusions.

1 reference

7 January 2021

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

1 reference

7 January 2021

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

1 reference

7 January 2021

Intracellular inclusions containing mutant alpha1-antitrypsin Z are propagated in the absence of autophagic activity

1 reference

7 January 2021

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

1 reference

7 January 2021

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

1 reference

7 January 2021

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

1 reference

7 January 2021

Loss of autophagy in the central nervous system causes neurodegeneration in mice

1 reference

7 January 2021

From Mallory to Mallory-Denk bodies: what, how and why?

1 reference

7 January 2021

Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies.

1 reference

7 January 2021

Keratin 8 overexpression promotes mouse Mallory body formation

1 reference

7 January 2021

Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates

1 reference

7 January 2021

The Alexander disease-causing glial fibrillary acidic protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alpha B-crystallin and HSP27

1 reference

7 January 2021

The cytoskeleton in neurodegenerative diseases

1 reference

7 January 2021

Protein aggregate myopathies

1 reference

7 January 2021

Expression of peripherin in ubiquinated inclusions of amyotrophic lateral sclerosis

1 reference

7 January 2021

The proteasome inhibitor, PS-341, causes cytokeratin aggresome formation

1 reference

7 January 2021

Autophagy modulates keratin-containing inclusion formation and apoptosis in cell culture in a context-dependent fashion.

1 reference

7 January 2021

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

1 reference

7 January 2021

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

7 January 2021

Studying simple epithelial keratins in cells and tissues.

1 reference

7 January 2021

Apoptosis generates stable fragments of human type I keratins

1 reference

7 January 2021

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

1 reference

7 January 2021

Bortezomib-induced severe hepatitis in multiple myeloma: a case report

1 reference

7 January 2021

Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial

1 reference

7 January 2021

Bortezomib or high-dose dexamethasone for relapsed multiple myeloma

1 reference

7 January 2021

Diurnal regulation of microsomal triglyceride transfer protein and plasma lipid levels

1 reference

7 January 2021

Aggresome formation in liver cells in response to different toxic mechanisms: role of the ubiquitin-proteasome pathway and the frameshift mutant of ubiquitin

1 reference

7 January 2021

Proteasome inhibition induces cytokeratin accumulation in vivo

1 reference

7 January 2021

The TOR pathway: a target for cancer therapy

1 reference

7 January 2021

Intermediate filament proteins and their associated diseases

1 reference

7 January 2021