Gene delivery to the juvenile mouse liver using AAV2/8 vectors (Q39991575)

16 September 2017

Gene delivery to the juvenile mouse liver using AAV2/8 vectors (English)

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16 September 2017

Sharon C Cunningham

1

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16 September 2017

Allison P Dane

2

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16 September 2017

Afroditi Spinoulas

3

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16 September 2017

Grant J Logan

4

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16 September 2017

Ian E Alexander

5

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16 September 2017

15 April 2008

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16 September 2017

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16 September 2017

16

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16 September 2017

1081-1088

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16 September 2017

6

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Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy

16 September 2017

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Long-term efficacy of adeno-associated virus serotypes 8 and 9 in hemophilia a dogs and mice

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Efficacy of an adeno-associated virus 8-pseudotyped vector in glycogen storage disease type II.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Administration-route and gender-independent long-term therapeutic correction of phenylketonuria (PKU) in a mouse model by recombinant adeno-associated virus 8 pseudotyped vector-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Efficient hepatic delivery and expression from a recombinant adeno-associated virus 8 pseudotyped alpha1-antitrypsin vector

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Correction of the biochemical and functional deficits in fabry mice following AAV8-mediated hepatic expression of alpha-galactosidase A.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Adeno-associated virus serotype 8 efficiently delivers genes to muscle and heart

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Long-term correction of murine glycogen storage disease type Ia by recombinant adeno-associated virus-1-mediated gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

The role of hepatocytes and oval cells in liver regeneration and repopulation

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Cell proliferation and renewal of normal hepatocytes and bile duct cells in adult mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

The kinetics of rAAV integration in the liver

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

DNA-dependent PK inhibits adeno-associated virus DNA integration

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Liver transduction with recombinant adeno-associated virus is primarily restricted by capsid serotype not vector genotype

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Rapid uncoating of vector genomes is the key to efficient liver transduction with pseudotyped adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

CD8(+) T-cell responses to adeno-associated virus capsid in humans

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Adeno-associated virus type 2 (AAV2) capsid-specific cytotoxic T lymphocytes eliminate only vector-transduced cells coexpressing the AAV2 capsid in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Zonation of metabolism and gene expression in liver.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Differential expression of apolipoprotein E messenger RNA within the rat liver lobule determined by in situ hybridization

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Mice expressing only the mutant APOE3Leiden gene show impaired VLDL secretion

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Regulation of enzymes of the urea cycle and arginine metabolism

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Prevention of systemic clinical disease in MPS VII mice following AAV-mediated neonatal gene transfer

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

AAV vector integration sites in mouse hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

No evidence for tumorigenesis of AAV vectors in a large-scale study in mice.

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Structure of the hepatic control region of the human apolipoprotein E/C-I gene locus

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Chimeric transcriptional control units for improved liver-specific transgene expression

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Development and optimization of a real-time quantitative PCR-based method for the titration of AAV-2 vector stocks

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Selective extraction of polyoma DNA from infected mouse cell cultures

1 reference

https://api.crossref.org/works/10.1038%2FMT.2008.72

7 January 2021

Identifiers

DOI

10.1038/MT.2008.72

1 reference

16 September 2017

1 reference