TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species (Q40020850)

16 September 2017

TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species (English)

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16 September 2017

reactive oxygen species

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Shi Jin

1

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PubMed ID

18218673

16 September 2017

Ramesh M Ray

series ordinal

2

1 reference

PubMed ID

18218673

16 September 2017

Leonard R Johnson

series ordinal

3

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16 September 2017

24 January 2008

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American Journal of Physiology - Gastrointestinal and Liver Physiology

16 September 2017

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16 September 2017

294

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16 September 2017

4

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16 September 2017

G928-37

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HO-2 provides endogenous protection against oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells.

16 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-alpha in IEC-6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Palmitate-induced apoptosis in cultured bovine retinal pericytes: roles of NAD(P)H oxidase, oxidant stress, and ceramide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

EGF blocks NADPH oxidase activation by TGF-beta in fetal rat hepatocytes, impairing oxidative stress, and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Cyclic mechanical strain increases reactive oxygen species production in pulmonary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Superoxide, H2O2, and iron are required for TNF-α-induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

TNF-alpha dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Reactive oxidant and p42/44 MAP kinase signaling is necessary for mechanical strain-induced proliferation in pulmonary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Molecular ordering of ROS production, mitochondrial changes, and caspase activation during sodium salicylate-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Regulation and measurement of oxidative stress in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Rac1 inhibits TNF-alpha-induced endothelial cell apoptosis: dual regulation by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

NF-kappaB activation by reactive oxygen species: fifteen years later

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Apoptotic pathways: ten minutes to dead

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Effect of local anaesthetics on mitochondrial membrane potential in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Regulation of NADPH oxidases: the role of Rac proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Rac1 mediates intestinal epithelial cell apoptosis via JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Role of NAD(P)H oxidase- and mitochondria-derived reactive oxygen species in cardioprotection of ischemic reperfusion injury by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Involvement of NADPH oxidase-mediated generation of reactive oxygen species in the apototic cell death by capsaicin in HepG2 human hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Intracellular generation of free radicals and modifications of detoxifying enzymes in cultured neurons from the developing rat forebrain in response to transient hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Redox-dependent downregulation of Rho by Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Tumor necrosis factor alpha stimulation of Rac1 activity. Role of isoprenylcysteine carboxylmethyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

NADPH oxidase and ERK signaling regulates hyperoxia-induced Nrf2-ARE transcriptional response in pulmonary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Mitochondrial density determines the cellular sensitivity to cisplatin-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Protein phosphatase 2A regulates apoptosis in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

The requirement for polyamines for intestinal epithelial cell migration is mediated through Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Antioxidant and anti-inflammatory efficacy of NAC in the treatment of COPD: discordant in vitro and in vivo dose-effects: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Molecular mechanisms of TNF-alpha-induced ceramide formation in human glioma cells: P53-mediated oxidant stress-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Effects of human milk and spermine on hydrogen peroxide-induced oxidative damage in IEC-6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Tumor necrosis factor-alpha generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Rac1 inhibits apoptosis in human lymphoma cells by stimulating Bad phosphorylation on Ser-75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Arrestin regulates MAPK activation and prevents NADPH oxidase-dependent death of cells expressing CXCR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

Oxygen JNKies: Phosphatases Overdose on ROS

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00219.2007

21 January 2018

Identifiers

DOI

10.1152/AJPGI.00219.2007

1 reference

16 September 2017

1 reference

PubMed ID

18218673